LONG^®EGF

Handling Recommendations     Product Specification

Recombinant human epidermal growth factor

LONG EGF is a potent analogue of human EGF already used in regulatory approved cell-based therapies. Used as a like-for-like replacement for native EGF or rhEGF, it comprises the human EGF amino acid sequence plus a 53 amino acid N-terminal extension peptide.

The recombinant growth factor can be used as a supplement for serum-free or low serum culture. It is also suitable for animal growth studies, general research and further manufacturing applications. Recombinant LONG EGF acts via the Erb-1 receptor and has applications in fibroblast cell culture. Synergistic effects have been observed with LONG®R3IGF-I in HEK293, PER.C6®, MDCK and HeLa cell lines. LONG EGF has also shown synergistic effect with LONG®TGF-α in keratinocyte differentiation and growth.

Key benefits - LONG EGF

• Animal-free, proprietary E-coli manufacturing process
• Like-for-like replacement for human, murine or recombinant EGF
• Used in approved and marketed cell-based therapies

Cell culture applications

• Stem and primary cell culture
• Vaccine cell culture

 For pricing and ordering information contact us at bioprocessing@repligen.com