To dialyze small 8- 30 ml volumes of delicate samples, dynamic dialysis is achieved by mounting the Spectra/Por® Tube-A-Lyzer onto the support rack of the KrosFlo® Research I Pump System, The system can be operated as a single unit or in parallel when multiple units are combined using a coupling bracket into a multi-unit device.
At process-scale, dynamic dialysis is used for the purification of macromolecules, proteins, nanoparticles, biomolecules, polymers (polypeptides, polysacharide, oligos), virus for vaccine and delicate/shear sensitive species. It is also ideal for the purification of viscous fluids and hydrogels (hyaluronic acid – HA) that cannot be filtered.
Dialysis membranes from Repligen include biotech-grade, standard-grade and custom membranes that can be used in both lab-scale and process-scale operations.