At Repligen bioprocessing seminars, thought leaders and professionals from around the world meet and review exciting new drivers of bioprocessing efficiency, learn from adopters of transformative technologies, evaluate risk landscapes and collaborate to help set the standards for modern bioproduction. 


To view speaker biographies and session abstracts,
click Expand All or the + next to each title.

Registration will begin at 9:00 a.m. Pre-registration is required to attend.


Implementation of single-use alternatives in tangential flow filtration (TFF), a critical step in concentration and diafiltration (buffer exchange), is becoming platform in downstream bioprocessing. Repligen TangenX™ SIUS™ Single-use Cassettes are the first purpose-built cassettes designed for tangential flow filtration. This presentation will demonstrate how deploying these innovative cassettes can help reduce filter cost by 80%, reduce labor costs by 50%, and reduce buffer and water usage by 75% when compared to traditional reusable cassettes.

Speaker Bio

Mike LaBreck.jpgMichael LaBreck is Director for Repligen TangenX™ TFF products at Repligen starting in December 2016.  Before that, he supported the TangenX™ product line at NovaSep 2008- 2016. He has over 20 years experience with tangential flow filtration applications support in the biopharmaceutical industry.  He has held various sales and applications engineering positions with Pall Corporation and GE Healthcare. Michael has a Bachelor of Science degree in Mechanical Engineering from Syracuse University. 


Viral clearance studies and scale down model development require a significant number of columns with known bed height and column performance characteristics.  Use of pre-packed columns for these studies represents an opportunity for significant time savings over packing columns in house for these critical studies.

Speaker Bio

nichols.jpgNathan Nicholes currently is a Downstream Process Development Scientist at KBI Biopharma in RTP, NC where he is involved in early phase process development, scale down model development, tech transfer and viral clearance studies in support of client projects. Dr. Nicholes received a BS in Chemical Engineering from the University of Oklahoma and a PhD in Chemical Engineering from Johns Hopkins University. 




There is no charge for attendance but registration is required. Seats are limited to end-users of bioprocessing tools and technologies.

Travel, accommodations, and incidental expenses are the responsibility of attendees. Lunch  will be served.

Sheraton Imperial Hotel

Room: Imperial 12
4700 Emperor Blvd I-40 at Exit 282, Page Rd
Durham, NC 27703



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