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Videos

Featured Video

Repligen Solutions from Gene to Therapy

Gene Therapy has immense potential to transform the lives of patients with genetic diseases. As demand for plasmids and viral vectors outpace capacity, a greater than 10-fold and potentially close to 100-fold increase in manufacturing efficiency for the gene therapy reagents is likely required to meet a demand curve that is increasing exponentially. Repligen solutions aim to meet the needs for optimized processes, higher yields, and improved process quality - setting new standards for modern scalable processes from gene to therapy.

An improved workflow for miniaturized pre-packed columns and automation

An improved workflow for miniaturized pre-packed columns and automation

A workflow for automated chromatography process development created by Repligen, Tecan, and Synthace enables efficient design, deployment, and analysis of downstream purification strategies. Miniaturized OPUS® RoboColumn® Columns reduce resource demand and allow for parallelization of experiments. In conjunction with robotic liquid handling from Tecan and purpose-built automation software from Synthace, RoboColumn® Column users can optimize yield, purity, and reproducibility for expediting downstream development. The synergistic benefits of OPUS® RoboColumn® Columns, Tecan robotics, and Synthace software will be demonstrated in the context of a case study that would be unapproachable using traditional methods.

XCell™ Lab System for Simplified and Scaled-down Intensification

XCell™ Lab System for Simplified and Scaled-down Intensification

XCell ATF® technology can expand bioprocess facility capacity and throughput with cell densities up 300 x 106 VCD/mL. The newly launched XCell™ Lab Controller System accelerates development of robust intensified processes at volumes as low as 0.5L, reducing media costs per run and facilitating advancement to manufacturing. The benefits of key features such as a 0.5L single-use device, permeate pressure recording, a pump-based control logic loop, support for two devices per controller and a modern smartphone-like software interface are be discussed.

New COVID-19 Affinity Resin Purifies SARS COV-2 Spike Protein in One Step

New COVID-19 Affinity Resin Purifies SARS COV-2 Spike Protein in One Step

The new NGL COVID-19 Spike Protein Affinity Resin from Repligen binds the SARS CoV-2 Spike Protein receptor binding domain (RBD) to yield exceptional purity in a single chromatography step. Developed in partnership with Navigo Proteins and Purolite Life Sciences , the product meets all expected requirements of a high-performance resin, including very high selectivity, high dynamic binding capacities and caustic stability over multi-cycle use. Design features of the resin and example performance data will be discussed.

Gene Therapy 2.0: Manufacturing Solutions that Work

Gene Therapy 2.0: Manufacturing Solutions that Work

This virtual seminar reviews the primary drivers of change, learnings from early adopters of transformative technologies, evaluations of risk landscapes and collaborations to help set the standards for Gene Therapy Manufacturing 2.0.

ARTeSYN and Repligen are now one

ARTeSYN and Repligen are now one

Together, Repligen and ARTeSYN now provide best-in-class single-use bioprocessing systems and industry-leading filtration and chromatography solutions.

Single-use TFF Systems
Single-use Viral Filtration Systems
Single-use Final Filtration and Bulk Filling Systems
Single-use Chromatography Systems

Repligen Solutions from Gene to Therapy

Repligen Solutions from Gene to Therapy

Repligen solutions for gene therapy aim to meet the needs for optimized processes, higher yields, and improved process quality - setting new standards for modern scalable processes from gene to therapy.

September 2020 | 3 minutes

About Repligen: Inspiring Advances in Bioprocessing

About Repligen: Inspiring Advances in Bioprocessing

Learn how Repligen is delivering innovative technologies and solutions that help set new standards in bioprocessing.

January 2019 | 2 minutes

Working at Repligen

Working at Repligen

Listen to Repligen employees talk about what it's like to work at Repligen.

January 2019 | 2 minutes

Technology-ready processes for Gene Therapy Manufacturing 2.0

Technology-ready processes for Gene Therapy Manufacturing 2.0

Repligen is ready to partner with gene therapy developers and manufacturers, providing technology breakthroughs and high impact solutions for plasmid and viral vector manufacturing.

May 12, 2020 | 11 minutes
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