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First and Only AAV Serotype-specific NaOH regenerable resins

AVIPure® - AAV Affinity Resins provide capture step purification of adeno-associated virus (AAV) 2, 8, and 9 vectors with potential alkaline clean-in-place (CIP) regeneration for improved process economics. A 50 µm cross-linked agarose matrix bead ensures compatibility with standard bioprocess columns and flow rates (3 bar at 300 cm/hour.​​​​​​)​

  • Clean-in-place with 0.5 M NaOH over 20 cycles​
  • Achieve high DBC​
    • >1 x 1014  vp/mL DBC with 1 minute residence time​​
    • >1 x 1015  vp/mL DBC with 4 minute residence time​​
  • Run high flow rates 3 bar at >300 cm/hr (2.6 x 20 cm column pressure packed at 4 bar)
  • Available pre-packed in OPUS® Columns

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