product features

High Performance

Quality Manufacturing

LONG® EGF – Power Your Cell Cultures

Enhance cell proliferation, viability, and culture longevity with LONG® EGF, a recombinant analog of human epidermal growth factor (EGF) optimized for serum-free and low-serum systems. Designed for fibroblast cells, epithelial cells, therapeutic cell culture, keratinocyte growth, and cell-based vaccine production, it delivers consistent, animal-free support for high-performance mammalian cell cultures.

Why LONG® EGF?

  • Receptor-specific activity: Activates the ErbB-1 (EGF) receptor, triggering mitogenic signaling pathways that promote cell division, survival, and metabolic activity
  • Synergy with IGF: Works in combination with LONG® R3 IGF-I to enhance proliferation, cell density, and productivity in HEK293, MDCK, and HeLa cultures
  • Robust performance in serum-free systems: Maintains viability and functional activity in chemically defined media, minimizing oxidative stress and apoptosis
  • Animal-free, recombinant production: Proprietary E. coli fermentation ensures reproducible activity without serum-derived variability or contamination risks

Bioassay Dose-response curve of LONG® EGF in proliferation bioassay using Balb/3T3 cells and luminescence measurements (RLU). Red line: LONG®EGF, Green line: Diluent.

Unlock cell growth & productivity

Request a Sample today of LONG® EGF to test with your cell cultures to see how this cell culture supplement can help improve cell culture performance, productivity and product quality. Start improving your performance today.

Request a Sample

LONG® EGF Product Quality

LONG® EGF is a recombinant analog of human epidermal growth factor (EGF) designed to support consistent cell growth and differentiation in therapeutic cell culture applications. Developed as a like-for-like replacement for native or recombinant human EGF (hEGF), LONG® EGF delivers reliable biological activity while maintaining a completely animal-free process.
Produced through a proprietary Escherichia coli fermentation process, LONG® EGF provides exceptional purity, batch-to-batch consistency, and quality suitable for use in regulatory-approved cell-based therapies.

Key Features

  • Manufactured to ISO 9001 standards
  • Animal-free, proprietary E. coli manufacturing process
  • Consistent, high-purity recombinant protein
  • Like-for-like replacement for human, murine, or recombinant EGF

Dose-response curve of LONG®EGF in proliferation bioassay using Balb/3T3 cells and luminescence measurements (RLU). Blue line: LONG®EGF, Green line: Diluent sample without EGF.

Formats
Lyophilized powder, dried from 10 mM hydrochloric acid (HCl) under nitrogen at slight vacuum (~25 kPa)

  • 1 mg
  • 20 mg

Storage

  • 1 mg: Storage and ship 2-8°C
  • 20 mg: Storage at -20°C and shipped frozen