LONG® EGF Cell Culture Supplement
Supports cell growth, proliferation, and viability in cell-based therapies with a recombinant, animal-free EGF analog.
High Performance
LONG EGF Product Quality
LONG® EGF – Power Your Cell Cultures
Enhance cell proliferation, viability, and culture longevity with LONG® EGF, a recombinant analog of human epidermal growth factor (EGF) optimized for serum-free and low-serum systems. Designed for fibroblast cells, epithelial cells, therapeutic cell culture, keratinocyte growth, and cell-based vaccine production, it delivers consistent, animal-free support for high-performance mammalian cell cultures.
Why LONG® EGF?
- Receptor-specific activity: Activates the ErbB-1 (EGF) receptor, triggering mitogenic signaling pathways that promote cell division, survival, and metabolic activity.
- Synergy with IGF: Works in combination with LONG® R3 IGF-I to enhance proliferation, cell density, and productivity in HEK293, MDCK, and HeLa cultures.
- Robust performance in serum-free systems: Maintains viability and functional activity in chemically defined media, minimizing oxidative stress and apoptosis.
- Animal-free, recombinant production: Proprietary E. coli fermentation ensures reproducible activity without serum-derived variability or contamination risks.
Bioassay Dose-response curve of LONG® EGF in proliferation bioassay using Balb/3T3 cells and luminescence measurements (RLU). Red line: LONG®EGF, Green line: Diluent.
Unlock cell growth & productivity
Request a Sample today of LONG® EGF to test with your cell cultures to see how this cell culture supplement can help improve cell culture performance, productivity and product quality. Start improving your performance today.
LONG® EGF Product Quality
LONG® EGF is a recombinant analog of human epidermal growth factor (EGF) designed to support consistent cell growth and differentiation in therapeutic cell culture applications. Developed as a like-for-like replacement for native or recombinant human EGF (hEGF), LONG® EGF delivers reliable biological activity while maintaining a completely animal-free process.
Produced through a proprietary Escherichia coli fermentation process, LONG® EGF provides exceptional purity, batch-to-batch consistency, and quality suitable for use in regulatory-approved cell-based therapies.
Key Features
- Manufactured to ISO 9001 standards
- Animal-free, proprietary E. coli manufacturing process
- Consistent, high-purity recombinant protein
- Like-for-like replacement for human, murine, or recombinant EGF
Dose-response curve of LONG®EGF in proliferation bioassay using Balb/3T3 cells and luminescence measurements (RLU). Blue line: LONG®EGF, Green line: Diluent sample without EGF.
Formats
Lyophilized powder, dried from 10 mM hydrochloric acid (HCl) under nitrogen at slight vacuum (~25 kPa)
- 1 mg
- 20 mg
Storage
- 1 mg: Storage and ship 2-8°C
- 20 mg: Storage at -20°C and shipped frozen
Solutions
Manufacturing Centers of Excellence
Repligen develops and manufactures products for the biopharmaceutical industry under an ISO 9001 quality management system. We focus on the timely delivery of high quality, consistent and robust products, to ensure business continuity for our customers.
Repligen manufacturing sites are located in Massachusetts, California, and New Jersey in the United States and in Sweden, France, The Netherlands, Germany and Estonia.
Customer First.
Support is part of the Repligen DNA. Our goal is to provide exceptional customer experience, and to support the efficient and successful adoption and implementation of all Repligen products and services.
- Field Application Support
- Customer Service
- Field Service Engineers
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