Revolutionizing Single-Use Mixing 

The ProConnex MixOne RG-X employs the trusted performance of the patented Metenova Zero Gravity Mixing technology now optimized for single-use applications. This cutting-edge system offers unmatched performance, ease of use, and scalability for both Upstream and Downstream bioprocessing professionals seeking cost-effective, efficient, and easy-to-deploy solutions.

product features

Superior Mixing with Confidence

Metenova Zero Gravity Mixing Technology

Rheology Optimized Vessel Geometry

Low Shear & High-Efficiency Mixer

Scalability in Every Way

Geometric Scalability 

Hybrid Scalability 

Operational Scalability 

Outstanding User Experience

Load. Lock. Mix. Simplicity 

Intuitive User Interface 

Modular Design

Safe and Easy Installation

Smart, Sustainable Mixing.

Reclaim magnets. Reduce waste.

Join us to drive sustainable innovation

Scale with certainty across workflows and platforms.

Confident Scale-up. Seamless Flexibility. 

The ProConnex® MixOne RG-X is purpose-built for consistent performance from development to production, empowering you to scale smarter and faster.

Geometric Scalability: 50L to 3,000L
  • Optimized geometry and mixer design for uniform scale-up
Hybrid Scalability: Single-use to 30,000L stainless steel
  • Same Zero-Gravity mixing tech for hybrid scalability across platforms
Operational Scalability: One drive, many vessels
  • Single drive powers multiple vessels, saving time and reducing errors
  • Built-In Efficiency: Lower risk, lower cost
  • Simplified design minimizes risk and total cost of ownership
Versatile technology for consistent, high-quality results.

Superior Mixing. Unmatched Performance​.

  • Zero Gravity Technology: High-efficiency ​impeller for superior outcomes​
  • Optimized Vessel Design: Cylindric shape and off-center mixing for maximum efficiency​
  • Gentle, Effective Mixing: Protects ​sensitive biologics and handles ​high-viscosity solutions​
  • Precision Mixing: from ​sensitive biologics to ​demanding processes
  • Versatile Compatibility: ​Supports a wide range of ​vessel sizes and formulations​
Speed, safety, and total control from day one. 

Simplified Bioprocessing. Empower Operators.

Engineered around the operator, this single-use mixing platform makes complex bioprocessing feel intuitive and efficient. With its “Load, Lock, and Mix” setup and user-friendly interface, it simplifies every step – from installation to batch execution. Designed to reduce operator error, streamline training, and support sustainability initiatives, the system delivers a modern workflow experience that’s both practical and rewarding to use. 

  • Fast Setup: Load, lock, and mix in minutes
  • ​Intuitive Control: Easy recipe creation and adjustments 
  • Error Reduction: Simplify training, reduce risks
play icon video poster
play icon video poster

Smarter Mixing for a more Sustainable Process

Our patented Zero – G mixing technology now features enhanced traceability – allowing Repligen to monitor the magnetic life of each mixer for greater process control.

  • Safely remove and reclaim magnets with our patent-pending process to support a more sustainable workflow
  • Connect with us to learn how you can be part of this next-generation, eco-conscious solution

ProConnex MixOne RG-X Bag 

Repligen ProConnex RG-V Film is engineered with precision and expertise, this 5-layer, 14 mil thick film sets the gold standard for single-use quality and reliability. From upstream to downstream bioprocessing applications, ProConnex RG-V Film serves as the basis for clean, leakproof single-use bag assemblies, used to construct flexible containment solutions including customizable ProConnex 2D and 3D bags.

  • Leak and puncture resistant
  • Excellent flex crack resistance
  • Optimal gas and water vapor barrier properties
  • Low coefficient of friction outer layer for enhanced durability and ease of installation
  • Non-animal origin formulation
  • Clean and accurate cast extrusion
  • Full BPoG extractables profile available
ProConnex MixOne RG-X Bag  
Bag Repligen ProConnex® RG-V Film
Impeller Magnets encased in polypropylene
Powder port Polyethylene TC 3" / TC 4"
Port sizes Polyethylene 1/8" - 1"

Repligen ProConnex® RG-V Film is a single-ply, 5-layer, 14 mil thick film developed specifically to meet the stringent quality standards of upstream and downstream single-use bioprocessing applications.

Click the + icons to discover the different layers of the ProConnex RG-V Film