With a culture of innovation, and focused on cost and process efficiencies, Repligen specializes in applications of technologies and solutions that help set new standards in perfusion, process intensification, enhanced vector titer and recovery yield, continuous manufacturing, and more.
Bioprocess intensification is defined as a significant step increase in output relative to cell concentration, time, reactor volume or cost, resulting in improvements in productivity, environmental and economic metrics.
ATMP
Advanced Therapy Medical Products (ATMP) have immense potential to transform the lives of patients with genetic diseases. Repligen partners with developers and manufacturers, providing technology breakthroughs and high impact solutions for plasmid and viral vector development and manufacturing.
Ultrafiltration | Diafiltration
Used in nearly every bioprocessing workflow, ultrafiltration/diafiltration (UF/DF) is a critical purification process, using tangential flow filtration (TFF), prior to final drug formulation.
Continuous Manufacturing
FROM BATCH TO CONTINUOUS
Continuous manufacturing is a method for manufacturing pharmaceutical products from end-to-end on a single, uninterrupted production line. The aim is to eliminate batch inefficiencies that result in process stoppages, long hold times, and sub-optimal facility utilization.
Process Analytics
Slope Spectroscopy® at-line and in-line protein concentration monitoring systems, and ligand-specific ELISA Kits, ensure that products meet required Process Analytical Technology (PAT) specifications.