Products
Protein A Ligands
LEADER IN PROTEIN A LIGAND MANUFACTURING SINCE 1985.
Most of the world's commercial monoclonal antibodies are purified using native and recombinant Protein A ligands manufactured by Repligen.
rSPA - Native Recombinant Staphylococcal Protein A Ligand
rSPA –Native Recombinant Staphylococcal Protein A Ligand – is the most advanced non-mutant Protein A ligand available from Repligen. The combination of performance and purity to native Protein A and outstanding economics and supply chain security, makes rSPA the automatic first choice for all new Protein A ligand applications.
- Contains the same amino acid sequence and molecular mass as the native Protein A sourced from S. aureus
- Manufactured with animal-free materials
Native Protein A Ligand
Native Protein A is a purification ligand used to isolate IgG from crude protein mixtures. It binds with high affinity to the Fc region of IgG's. When immobilized on a matrix, e.g; Sepharose, Protein A (native) can be used to isolate IgG from crude protein mixtures.
Native Protein A meets the strictest demands of drug manufacturers in terms of purity, reproducibility, binding capacity, specificity and other key measures critical to the quality of downstream processes.
- Reliable performance: Fc specific binding to IgG
- Guaranteed purity: > 95% purity by SEC
- Activity: > 95% IgG-binding activity
- Not purified by hIgG affinity
- Produced according to cGMP
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