ProConnex® 2D bags support a wide range of applications, including cell culture media and buffer management, fluid transfer, sampling, storage, transportation, and intermediate product hold. Designed for closed-system processing, they help maintain fluid integrity while reducing contamination risk throughout upstream and downstream bioprocessing workflows.

From process development to commercial manufacturing, ProConnex® 2D bags provide a reliable solution for handling critical bioprocess fluids with confidence. Available as standard off-the-shelf products or configured options tailored to your needs. Contact a sales specialist for more information.

product features

Protect product quality with secure, closed-system fluid handling

Improve process efficiency with ready-to-use, customizable assemblies

Scale with confidence from development through commercial production

ProConnex® RG-V Film

Engineered with precision and expertise, this 5-layer, 14 mil thick film sets the gold standard for single-use quality and reliability. From upstream to downstream bioprocessing applications, ProConnex RG-V Film serves as the basis for clean, leakproof single-use bag assemblies, used to construct flexible containment solutions including customizable ProConnex 2D and 3D bags.

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From Production to Performance – Built for Reliability

Automated manufacturing of 2D bioprocess containers delivers the consistency, quality, and scalability biomanufacturers need. Precision automation of cutting, welding, assembly, and testing reduces variability, enhances traceability, and supports a reliable supply of single-use systems.

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A Better Way to Protect Critical Bioprocess Fluids

Repligen and Single Use Support® have partnered to help biomanufacturers reduce risk and protect valuable materials throughout freezing, storage, transport, and thawing. By combining ProConnex® 2D bags with the RoSS® Shell platform, customers gain a proven solution that enhances product protection, improves process robustness, and delivers greater confidence in cold chain operations.

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RoSS® shell for Repligen ProConnex® 2D bag brochure

ProConnex® 2D Bioprocess Containers

Product # Description Volume Port Measurements and End Treatments
FP2B100052 ProConnex 2D BAG, ASEPTIC (RG-V) 25 mL
  • 1 x 1/8 in Luer Needle-free-swabable sample port
  • 1 x 1/4 in AseptiQuik® G
FP2B100055ProConnex 2D BAG, ASEPTIC (RG-V) 50 mL
  • 1 x 1/8 in Luer Needle-free-swabable sample port
  • 1 x 1/4 in AseptiQuik G
FP2B100048 ProConnex 2D BAG, ASEPTIC (RG-V) 150 mL
  • 1 x 1/8 in Luer Needle-free-swabable sample port
  • 1 x 1/4 in AseptiQuik G
FP2B100051 ProConnex 2D BAG, ASEPTIC (RG-V) 250 mL
  • 1 x 1/8 in Luer Needle-free-swabable sample port
  • 1 x 1/4 in AseptiQuik G
FP2B100054 ProConnex 2D BAG, ASEPTIC (RG-V) 500 mL
  • 1 x 1/8 in Luer Needle-free-swabable sample port
  • 1 x 1/4 in AseptiQuik G
FP2B100049 ProConnex 2D BAG, ASEPTIC (RG-V) 1 L
  • 1 x 1/8 in Luer Needle-free-swabable sample port
  • 2 x 1/4 in AseptiQuik G
FP2B100053 ProConnex 2D BAG, ASEPTIC (RG-V) 2 L
  • 1 x 1/8 in Luer Needle-free-swabable sample port
  • 2 x 1/4 in AseptiQuik G
FP2B100056 ProConnex 2D BAG, ASEPTIC (RG-V) 5 L
  • 1 x 1/4 in Luer Needle-free-swabable sample port
  • 2 x 3/8 in AseptiQuik G
FP2B100047 ProConnex 2D BAG, ASEPTIC (RG-V) 10 L
  • 1 x 1/4 in Luer Needle-free-swabable sample port
  • 2 x 3/8 in AseptiQuik G | 1 x 1/2 in plug
FP2B100050 ProConnex 2D BAG, ASEPTIC (RG-V) 20 L
  • 1 x 1/4 in Luer Needle-free-swabable sample port
  • 2 x 3/8 in AseptiQuik G | 1 x 1/2 in plug
FP2B100063 ProConnex 2D BAG, W/ MPC & LUER (RG-V) 25 mL
  • 1 x 1/8 in Luer Female
  • 1 x 1/4 in MPC Female
FP2B100059 ProConnex 2D BAG, W/ MPC & LUER (RG-V) 50 mL
  • 1 x 1/8 in Luer Female
  • 1 x 1/4 in MPC Female
FP2B100067 ProConnex 2D BAG, W/ MPC & LUER (RG-V) 150 mL
  • 1 x 1/8 in Luer Female
  • 1 x 1/4 in MPC Female
FP2B100064 ProConnex 2D BAG, W/ MPC & LUER (RG-V) 250 mL
  • 1 x 1/8 in Luer Female
  • 1 x 1/4 in MPC Female
FP2B100061 ProConnex 2D BAG, W/ MPC & LUER (RG-V) 500 mL
  • 1 x 1/8 in Luer Female
  • 1 x 1/4 in MPC Female
FP2B100066 ProConnex 2D BAG, W/ MPC & LUER (RG-V) 1 L
  • 1 x 1/8 in Luer Female
  • 2 x 1/4 in MPC Female
FP2B100062 ProConnex 2D BAG, W/ MPC & LUER (RG-V) 2 L
  • 1 x 1/8 in Luer Female
  • 2 x 1/4 in MPC Female
FP2B100060 ProConnex 2D BAG, W/ MPC & LUER (RG-V) 5 L
  • 1 x 1/8 in Luer Female
  • 2 x 3/8 in MPC Female
FP2B100068 ProConnex 2D BAG, W/ MPC & LUER (RG-V) 10 L
  • 1 x 1/4 in Luer Female
  • 2 x 3/8 in MPC Female
  • 1 x 1/2 in MPC Female
FP2B100065 ProConnex 2D BAG, W/ MPC & LUER (RG-V) 20 L
  • 1 x 1/4 in Luer Female
  • 2 x 3/8 in MPC Female
  • 1 x 1/2 in MPC Female