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Inspiring advances in bioprocessing

Introducing TFDF™ Technology: Novel High Flux Single-use Filtration for Fed-Batch Clarification

Set new standards in clarification


"The DNA of our company is absolutely around customer first. Listening to what our customers are doing, what their needs are, what their pain points are, touches every facet of what we do."

Tony Hunt, President and CEO        

Scale Up with OPUS:

Introducing OPUS 80R

OPUS® 80R is the first and only pre-packed column enabling purification of over 10 kilograms of protein in a single cycle.

OPUS® Pre-packed Chromatography Columns offer unparalleled flexibility in media choice, application and size. Applying the most advanced pre-packed chromatography column technology available today, OPUS® columns are ready-to-use alternatives to traditional self-packed columns.

Configure Your ColumN Your Way

High Productivity Harvest

High Productivity Harvest (HPH) is a novel application developed by Repligen that enables you to harvest a fed-batch bioreactor in a fully sterile manner, while eliminating both centrifugation and depth filtration operations typically used for harvest/clarification. A single stage, closed process with XCell™ ATF, the HPH application provides:

  • Higher yields compared to traditional harvest technologies

  • Up to a two-fold increase in protein production

  • A 0.2µm clarified harvest ready for either batch or continuous chromatography


KrosFlo® KR2i with KONDUiT

A proven turnkey benchtop system for lab-scale process development, the KrosFlo® KR2i Tangential Flow Filtration (TFF) System is fully integrated and easy to use with walkaway automation.

  • 2ml - 15L volume
  • 13 cm2 - 5000 cm2 filtration area

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Join the REpligen Team

With offices and facilities in multiple locations, we are always looking for smart, driven, and enthusiastic individuals to join our growing team.

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