KrosFlo® TFF Systems
Turnkey systems for tangential flow filtration (TFF), KrosFlo® Systems are compatible with single-use hollow fiber filters and/or flat sheet cassettes, modernizing how UF/DF is performed at every stage from process development to large-scale manufacturing.
Discover your next KrosFlo® TFF System
Adored and economical with good automation 5mL - 500L
Revered for its simplicity and capability, the Repligen KrosFlo® KR2i, KMPi, RPM and FS family of systems are some of the most widely used lab scale TFF platforms in the world.


KrosFlo® KR2i TFF System
Single-use fully integrated benchtop TFF system for use in lab scale process development ranging from 2mL - 15L. Compatible with hollow fiber or flat sheet filters, this system offers many user-defined set-point controls so you can run complex applications in fully-automated modes.

KrosFlo® KR2i RPM™ System
TFF with In-Line Protein Concentration Management
Monitor concentration in real time during your UF/DF run. Featuring in-line protein concentration management, control your process with the power of the KrosFlo® KR2i TFF System and insights from the integrated CTech™ FlowVPX® System.
Highly configurable, small footprint with better automation 200L - 5000L
Popular in pilot scale and flexible manufacturing environments, the KrosFlo® KTF series offers unrivalled configurability to support multiple scales, unit operations and solutions while retaining a small footprint. Customization available upon request.
cGMP compliant with end-to-end automation 1L - 2000L
Ideal for mRNA and gene therapy production, KrosFlo® RS TFF series are industrial grade, fully automated cGMP manufacturing systems designed to take on an era of new modalities. Customization available upon request.