Sustainability
Materiality
At Repligen, we value monitoring emerging issues material to our business and our value chain, assessing related topics according to new information and evolving stakeholder expectations. We aim to review our Materiality Matrix annually to ensure that our team is focused on the most important issues and opportunities for impact. This helps us to stay closely aligned with stakeholder priorities and relevant regulations that influence the rapidly evolving bioprocessing industry.
The DMA identified 34 material impacts, risks, and opportunities (IROs), mapped to seven ESRS topical standards and selected entity-specific topics. These include 11 positive impacts, 10 negative impacts, 9 risks, and 4 opportunities—creating clear line-of-sight to where we can protect value, improve resilience, and drive long-term value creation.
Material Topics
Environmental
- Climate Change (ESRS E1)
- Pollution, including micro-plastics
(ESRS E2) - Resource Use and Circular Economy (ESRS E5)
Social
- Own Workforce (ESRS S1)
- Affected Communities (ESRS S3)
- Consumers and End-Users (product quality and safety) (ESRS S4)
Governance
- Business Conduct (ESRS G1)
- Cybersecurity (entity-specific)
- Responsible Technology Advancement, including AI (entity-specific)
- GHG Protocol Guidance was used for all emissions accounting, and market-based emission factors were utilized for the calculations.
- The U.S. Environmental Protection Agency (EPA) Emissions and Generation Resource Integrated Database (eGRID) and EPA Energy Information Administration (EIA) data were used to prepare our emissions inventories.
- EPA Global Warming Potential (GWP) values were used to standardize all emissions by carbon dioxide equivalents (CO2e).
- Energy usage and GHG emissions metrics are based on utility invoices of purchased energy, best estimates from property managers of shared rental spaces and in-house calculations from site-level data.
- The annual impact of direct renewable electricity purchases and renewable energy credits (RECs) on our total GHG emissions is based on aggregate market-based site-level data.
- Water withdrawal metrics are based on utility invoices and used as a proxy for consumption data. At our one site that is supported by well water, metrics are derived from expected baseline usage.
- Water discharge metrics are tracked for water that is used in manufacturing processes and treated before discharge.
- Waste metrics are predicated on hauler invoices, regular service provider reporting and in-house calculations.
- Employee-related data covers all Repligen sites, unless otherwise indicated.
- Annual voluntary commuting surveys directly inform our global Scope 3 category 7 (Employee Commuting) emissions data.
The Repligen ESG Ambassador network is responsible for collecting and monitoring site-level data on an ongoing basis while our corporate Sustainability team oversees uploads to our financial-grade ESG software platform.
Other than audited financial data, the content of this report has not been externally verified. However, the feasibility of third-party assurance is under evaluation for future installments of our corporate sustainability report.
Any financial data sets in this report are historical only and have been fully audited by our independent registered public accounting firm based on criteria established in Internal Control — Integrated Framework issued by the Committee of Sponsoring Organizations of the Treadway Commission (2013 framework). All financial information in this report is limited to continuing operations and is reported in U.S. dollars.
For more information about Repligen Corporation’s approach to sustainability and ESG reporting, email us at sustainability@repligen.com.
