Materiality
At Repligen, we value monitoring emerging issues material to our business and our value chain, assessing related topics according to new information and evolving stakeholder expectations. We aim to review our Materiality Matrix annually to ensure that our team is focused on the most important issues and opportunities for impact. This helps us to stay closely aligned with stakeholder priorities and relevant regulations that influence the rapidly evolving bioprocessing industry.
In 2024, we continued to lead and participate in numerous stakeholder communications across the business with key customers, critical suppliers, leading institutional investors and employee resource groups. This engagement helped us understand their interests, priorities, targets and challenges through the increasingly relevant lens of sustainability. The Materiality Matrix on this page summarizes Repligen Corporation’s materiality assessment, which aligns with our foundational four pillars of sustainability, the 4Ps first introduced in our inaugural 2020 corporate sustainability report, “Committed to Making a Difference.”
Scope 3 Materiality
The second table on this page summarizes our assessment of material Scope 3 emissions categories. Here we highlight the 11 categories, of 15 total categories, that are material to Repligen. We started reporting on two of these categories, category 6 (Business Travel) and category 7 (Employee Commuting), in our inaugural 2020 report. In our 2022 report, we added emissions data for seven additional categories, bringing the total to nine. And with our 2024 report, we have included partial data for the two remaining material categories, category 11 (Use of Sold Products) and category 12 (End-of-Life Treatment of Sold Products). While these last two emissions inventories include data for select Repligen products only, significant progress was made toward building out the process map for other product lines. We look forward to elevating our Scope 3 emissions reporting for 2025 and beyond.
Materiality Matrix
In 2024, we reviewed the materiality assessment and Scope 3 categories reflected on this page according to our 4Ps and reaffirmed them. Additionally, we will perform a double materiality assessment in 2025 to update this information and align with the European Union’s new Corporate Sustainability Reporting Directive (CSRD).
matrix
Material to Repligen
COMMUNITIES | CUSTOMERS | EMPLOYEES | INVESTORS | SUPPLIERS | |
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PrinciplesWorking Responsibily |
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Business Ethics & Compliance | ![]() |
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Enterprise Risk Management | ![]() |
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Financial Integrity | ![]() |
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Cybersecurity & Data Privacy | ![]() |
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Partner (Supplier) Ethics & Compliance | ![]() |
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PeopleCaring About Our Employees and Communities |
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Health, Safety & Well-Being | ![]() |
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Diversity, Equity & Inclusion | ![]() |
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Employee Attraction, Development & Retention | ![]() |
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Community Engagement & Impact | ![]() |
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Labor Practices | ![]() |
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ProductInnovating Through a Sustainability Lens |
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Innovation | ![]() |
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Supply Chain Management | ![]() |
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Product Quality & Safety | ![]() |
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Product Design & Lifecycle Management | ![]() |
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PlanetProtecting the Environment |
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Environmental Impact | ![]() |
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Energy Use & Climate Impact | ![]() |
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Water Use | ![]() |
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Solid Waste Management | ![]() |
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Principles
Working Responsibly
COMMUNITIES | CUSTOMERS | EMPLOYEES | INVESTORS | SUPPLIERS | |
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Business Ethics & Compliance | ![]() |
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Enterprise Risk Management | ![]() |
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Financial Integrity | ![]() |
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Cybersecurity & Data Privacy | ![]() |
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Partner (Supplier) Ethics & Compliance | ![]() |
Material to Repligen
People
Caring About Our Employees and Communities
COMMUNITIES | CUSTOMERS | EMPLOYEES | INVESTORS | SUPPLIERS | |
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Health, Safety & Well-Being | ![]() |
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Diversity, Equity & Inclusion | ![]() |
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Employee Attraction, Development & Retention | ![]() |
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Community Engagement & Impact | ![]() |
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Labor Practices | ![]() |
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Material to Repligen
Product
Innovating Through a Sustainability Lens
COMMUNITIES | CUSTOMERS | EMPLOYEES | INVESTORS | SUPPLIERS | |
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Innovation | ![]() |
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Supply Chain Management | ![]() |
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Product Quality & Safety | ![]() |
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Product Design & Lifecycle Management | ![]() |
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Material to Repligen
Planet
Protecting the Environment
COMMUNITIES | CUSTOMERS | EMPLOYEES | INVESTORS | SUPPLIERS | |
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Environmental Impact | ![]() |
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Energy Use & Climate Impact | ![]() |
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Water Use | ![]() |
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Solid Waste Management | ![]() |
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Material to Repligen
scope 3 emissions categories
Material to Repligen
1 Purchased goods and services
2 Capital goods
3 Fuel- and energy-related activities
4 Transportation and distribution (upstream)
5 Waste generated in operations
6 Business travel
7 Employee commuting
8 Upstream leased assets
9 Transportation and distribution (downstream)
- 10 Processing of sold products
11 Use of sold products
12 End-of-life treatment of sold products
- 13 Downstream leased assets
- 14 Franchises
- 15 Investments
- GHG Protocol Guidance was used for all emissions accounting, and market-based emission factors were utilized for the calculations.
- The U.S. Environmental Protection Agency (EPA) Emissions and Generation Resource Integrated Database (eGRID) and EPA Energy Information Administration (EIA) data were used to prepare our emissions inventories.
- EPA Global Warming Potential (GWP) values were used to standardize all emissions by carbon dioxide equivalents (CO2e).
- Energy usage and GHG emissions metrics are based on utility invoices of purchased energy, best estimates from property managers of shared rental spaces and in-house calculations from site-level data.
- The annual impact of direct renewable electricity purchases and renewable energy credits (RECs) on our total GHG emissions is based on aggregate market-based site-level data.
- Water withdrawal metrics are based on utility invoices and used as a proxy for consumption data. At our one site that is supported by well water, metrics are derived from expected baseline usage.
- Water discharge metrics are tracked for water that is used in manufacturing processes and treated before discharge.
- Waste metrics are predicated on hauler invoices, regular service provider reporting and in-house calculations.
- Employee-related data covers all Repligen sites, unless otherwise indicated.
- Annual voluntary commuting surveys directly inform our global Scope 3 category 7 (Employee Commuting) emissions data.
The Repligen ESG Ambassador network is responsible for collecting and monitoring site-level data on an ongoing basis while our corporate Sustainability team oversees uploads to our financial-grade ESG software platform.
Other than audited financial data, the content of this report has not been externally verified. However, the feasibility of third-party assurance is under evaluation for future installments of our corporate sustainability report.
Any financial data sets in this report are historical only and have been fully audited by our independent registered public accounting firm based on criteria established in Internal Control — Integrated Framework issued by the Committee of Sponsoring Organizations of the Treadway Commission (2013 framework). All financial information in this report is limited to continuing operations and is reported in U.S. dollars.
For more information about Repligen Corporation’s approach to sustainability and ESG reporting, email us at [email protected].