Products Built to Move Bioprocessing Forward

From process development to commercial manufacturing, Repligen delivers integrated bioprocessing products that help manufacturers improve yield, reduce risk, simplify scale-up, and accelerate time to market.

Whether you are producing monoclonal antibodies, proteins, viral vectors, mRNA, pDNA, or new modalities, Repligen solutions are designed to support confident decisions and efficient execution across your workflow.

Repligen KrosFlo KR2i bioprocessing system with Mettler Toledo scales, FlowVPX inline detector, and Konduit controller, showing a tablet-based P&ID interface for process control
Why Repligen Products

Designed for Real Manufacturing Outcomes

Bioprocessing teams need more than individual components. They need technologies that work together, scale reliably, and support changing process demands.

Increase productivity
Across upstream and downstream operations

Ensure quality
Improve process consistency and product quality

Improve scalability
Simplify tech transfer and scale-up

Apply automation
Reduce manual intervention and complexity

Reduce risk
Strengthen data visibility and process control

Enable flexibility
Build flexible manufacturing capacity

Explore Repligen Products by Category

Repligen KrosFlo TFDF dual-column filtration system featuring ProConnex TFDF Flow Paths for high-flux bioprocessing and automated cell culture clarification.

Upstream Filtration

Improve cell retention, intensify upstream performance, and support higher productivity with proven filtration technologies.

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Repligen KrosFlo RS 30 filtration system with integrated touch-screen control and dual hollow fiber filters for automated downstream bioprocessing and protein concentration.

Downstream Filtration

Concentrate, clarify, and purify biologics with scalable tangential flow filtration solutions built for development through commercial manufacturing.

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Repligen KRM 10 Chromatography System featuring an integrated OPUS 20 pre-packed column and dual-screen digital interface for automated large-scale protein purification and downstream bioprocessing.

Chromatography

Increase purification efficiency with systems, pre-packed columns, and resins engineered for modern biologics manufacturing. 

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Repligen ProConnex MixOne RG-X single-use mixing system featuring Metenova Zero Gravity technology and RG-V film for sterile, low-shear bioprocessing and vaccine manufacturing.

Single -Use Fluid Management

Move, mix, store, and transfer critical process fluids with single-use solutions designed for speed, sterility, and operational flexibility.

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Repligen PATsmart SoloVPE Plus system using Variable Pathlength Technology (VPT) for rapid, buffer-free protein concentration measurement and automated UV-Vis spectroscopy in bioprocessing.

Process Analytics

Gain faster answers and stronger process control with real-time process analytical technology that drives confident decisions. 

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Repligen LONG R3 IGF-I and LONG EGF recombinant growth factors in glass vials for serum-free cell culture media supplementation and enhanced recombinant protein production.

Cell Culture Supplements

Support stronger upstream performance with growth factors designed to enhance cell culture productivity.

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Repligen rSPA recombinant Staphylococcal Protein A chromatography ligands for high-purity monoclonal antibody (mAb) purification and affinity resin development.

Ligands

Access trusted ligand technologies for chromatography and purification workflows.

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Repligen SpectraFlo Dynamic Dialysis system featuring a quad-column configuration for high-volume automated buffer exchange and sample purification in large-scale bioprocessing.

Dialysis Technologies

Reliable dialysis membranes and tubing for laboratory and production workflows.

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Disposable sterile surgical drapes for robotic-assisted surgery systems, designed to maintain a sterile field and protect equipment during minimally invasive robotic procedures.

Operating Room Disposables

Support sterile workflows, protect equipment, and improve procedural efficiency with these clinical single use solutions.

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Products by Modality

Built for Today’s Leading Modalities

Repligen products support a broad range of therapeutic platforms with scalable solutions tailored to modality-specific challenges.

Explore Modalities

3D molecular visualization of a monoclonal antibody (mAb) structure used in biologics development and therapeutic manufacturing.

Monoclonal Antibodies

Improve productivity, purification efficiency, and manufacturing consistency.

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3D molecular visualization of an adeno‑associated virus (AAV) vector used for gene therapy and viral vector delivery applications.

Viral Vectors

Support AAV, lentiviral, and next-generation vector production with intensified upstream and downstream solutions.

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3D molecular visualization of messenger RNA (mRNA) structure used in gene therapy, vaccines, and advanced biologics development.

mRNA

Enable flexible workflows for nucleic acid processing, purification, and scale-up.

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3D molecular visualization of circular plasmid DNA structure used in gene therapy, cell therapy, and advanced biomanufacturing workflows.

pDNA

Support rapid development and reliable manufacturing.

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3D molecular visualization of an antibody‑drug conjugate (ADC) structure used in advanced biologics and targeted therapeutic development.

ADC

Adapt faster with risk reducing technologies built for closed manufacturing processes.

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Integrated Solutions

Better Results When Products Work Together

Many customers need more than a standalone product. Repligen combines hardware, consumables, analytics, and application expertise to help create connected workflows that reduce complexity and improve execution.

Examples:

  • Perfusion and single-use flow paths
  • TFF and PAT technologies
  • Chromatography resins and pre-packed columns
  • Vector purification workflows
  • End-to-end scale-up strategies

 

Why customers choose Repligen

A Partner Focused on What Comes Next

Customers choose Repligen because they need solutions that perform now and remain flexible for what comes next.

Repligen helps teams move forward with:

  • Deep bioprocessing expertise
  • Scalable technologies
  • Practical implementation support
  • Global manufacturing and supply capability
  • Proven performance across commercial environments

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A diverse team of smiling bioprocessing scientists and laboratory engineers in white lab coats and safety goggles standing in a modern life sciences research facility.

Frequently Asked Questions

Repligen offers bioprocessing products across filtration, chromatography, fluid management, process analytics, affinity resins, ligands, cell culture supplements, and dialysis technologies.

Repligen products are used by biopharmaceutical companies, CDMOs, research organizations, and advanced therapy developers manufacturing biologic medicines and therapeutics.

Yes. Repligen provides solutions for viral vectors, plasmid DNA, mRNA, and other advanced modalities.

Yes. Many Repligen technologies are designed to support process development, pilot scale, and GMP commercial manufacturing.

Customers can browse by unit operation, modality, or speak with a Repligen expert for application guidance.

Find the Right Product for Your Process

Every process has different constraints, goals, and timelines. Repligen helps you evaluate options clearly and move forward with confidence.