Fluid management is how you design, control, and optimize the movement of fluids across your bioprocess—ensuring every transfer, mix, and hold step occurs under precise, controlled conditions. It is foundational for bioprocess efficiency, contamination control, and scalable biomanufacturing performance.

ProConnex Fluid Management Solutions include single-use assemblies, bioprocess containers and bags, sterile tubing and connectors, fluid path components, process hardware, advanced mixing systems, and single-use valves. Together, these solutions enable closed-system processing, sterile fluid transfer, and end-to-end single-use bioprocessing workflows across upstream and downstream applications.

Built as designed-for-purpose single-use fluid management solutions, ProConnex delivers flexible, scalable, and modular single-use systems that reduce contamination risk, eliminate cleaning validation, and accelerate changeovers. The result is improved batch consistency, operational efficiency, and cGMP compliance – supporting process intensification, flexible manufacturing, and rapid scale-up from development to commercial production.

Repligen PCx single‑use flow paths assembled for bioprocessing applications, showing tubing, connectors, and integrated process components.

ProConnex® Flow Paths

Expertly designed plug-and-play flow path

ProConnex® Flow Paths for TFF and Chromatography processes are single-use and engineered for optimum performance, reproducibility and time savings. System specific flow paths provide speed and reliability. Configured flow paths prioritize process requirements and sterility. ​

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Single‑use bioprocessing bottles and container systems designed for sterile fluid storage, transport, and handling across multiple process scales.

ProConnex® Bioprocess Containers

Including bottles, carboys, 2D bags, and 3D bags—provide flexible, scalable solutions for safe storage, transport, and handling of critical process fluids 

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Single‑use bioprocessing connectivity components including sanitary clamps, tubing connectors, and fluid handling interfaces.

ProConnex® Components

High-quality fluid management components—from connectors and fittings to tubing and sensors—enable secure, precise, and leak-free fluid transfer across your bioprocess. 

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Family shot of large tote, small tote, filter holder, and tubing cart

ProConnex® Process Hardware

Non-metallic process hardware—including totes, filter racks, and cleanroom furniture—supports organized, efficient, and contamination-controlled operations across your bioprocess environment. 

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Repligen ProConnex MixOne RGX single-use fluid management system for bioprocessing and sterile liquid mixing, featuring integrated ProConnex flow paths for closed-system pharmaceutical manufacturing.

ProConnex MixOne RG-X

Designed for versatility throughout the bioproduction workflow, the ProConnex® MixOne RG-X offers superior mixing with the patented performance of Metenova® Zero Gravity mixing technology, and ensures an outstanding user experience and scalability in all aspects. 

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Sanitary bioprocessing valves designed for precise fluid control in single‑use and stainless‑steel process systems.

ProConnex® Single-use Valves

Reliable, leak-free fluid control with precise flow regulation, reduced contamination risk, and seamless integration into closed, single-use systems. 

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Metenova® Stainless Steel Mixers

Metenova stainless steel mixers deliver aseptic, high-performance mixing through proven magnetic technology—ensuring reliable, contamination-free operation for critical bioprocess applications.

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Service

Expert support, installation, and lifecycle optimization to keep your bioprocess running at peak performance.

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Single-Use Technologies and Sustainability-by-Design in Biopharma Production

Single-use technologies are transforming biomanufacturing with greater flexibility, speed, and contamination control—but they also introduce sustainability challenges that must be addressed early in process design. By applying sustainability-by-design, life cycle thinking, and process intensification, biopharma companies can balance performance with environmental impact—driving more efficient, scalable, and responsible production.

 

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