Fluid management is critical within and between every unit operation in upstream and downstream biopharmaceutical manufacturing processes. Each touchpoint, regardless of size, presents a risk of failure as well as an opportunity for step advances in process economics and process efficiency. 

Repligen fluid management solutions include state-of-the-art single-use components, and innovative storage and transfer equipment.

  • Conveys fluid across unit operations
  • Includes equipment and consumables
  • Grows, processes and conveys biotherapeutics and process liquids
  • Connects the unit operations and stores material
  • Includes bags, bottles, tubing, totes and other components
  • Excludes processing equipment
Sanitary bioprocessing valves designed for precise fluid control in single‑use and stainless‑steel process systems.

Single-use Valves

Single-use valves add ease and disposability to traditional valve formats. Configurable and modular, they are designed as sanitary drop-in replacements to standard diaphragm and arterial process valves.

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Family shot of large tote, small tote, filter holder, and tubing cart

Non-metallic Process Equipment

Repligen non‑metallic process equipment offer cost‑effective alternatives to stainless steel, with flexible configurations and high‑quality Class VI TSE/BSE‑free materials.

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Single‑use bioprocessing bottles and container systems designed for sterile fluid storage, transport, and handling across multiple process scales.

Single-use Containment Solutions

Flexible and rigid single‑use containment for bioprocessing, designed to optimize handling and transfer of high‑value liquids using bottles, carboys, and 2D/3D bags.

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Technician in a cleanroom handling flexible bioprocessing tubing during laboratory assembly.

Fluid Transfer Solutions

Optimize transfer of high-value liquids

ProConnex® tubing and tubing management solutions are specifically manufactured to meet the stringent physical and quality requirements of biopharmaceutical applications.

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Repligen PCx single‑use flow paths assembled for bioprocessing applications, showing tubing, connectors, and integrated process components.

ProConnex® Flow Paths

Expertly designed plug-and-play flow path

ProConnex® Flow Paths for TFF and Chromatography processes are single-use and engineered for optimum performance, reproducibility and time savings. System specific flow paths provide speed and reliability. Configured flow paths prioritize process requirements and sterility. ​

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ProConnex® MixOne CB-X

A cutting-edge single-use mixing system for bioprocess products that boasts exceptional performance for shear-sensitive substances.

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Single‑use bioprocessing connectivity components including sanitary clamps, tubing connectors, and fluid handling interfaces.

Connectivity

Security at the point of connection

Hundreds of connection points are present throughout your workflow, each presenting risk of failure. ProConnex® single-use connectivity solutions are purpose-built for bioprocessing applications, optimizing fluid transfer within and between critical process steps.

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Repligen ProConnex MixOne RGX single-use fluid management system for bioprocessing and sterile liquid mixing, featuring integrated ProConnex flow paths for closed-system pharmaceutical manufacturing.

ProConnex MixOne RG-X

Designed for versatility throughout the bioproduction workflow, the ProConnex® MixOne RG-X offers superior mixing with the patented performance of Metenova® Zero Gravity mixing technology, and ensures an outstanding user experience and scalability in all aspects. 

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