XCell® ATF Devices and Controllers
XCell® ATF Systems simplify and fast-track upstream intensification by providing an integrated solution consisting of an XCell® ATF Device, XCell® ATF Controller, software, tubing, pressure sensors and accessories. The family of Systems supports diverse applications across development from 1L to 5000 L.
XCell ATF® Device Size Selection Guide
Presented are hollow fiber filter areas, XCell ATF® Pump volumes, and typical bioreactor working volumes paired with each XCell ATF® Device. Actual capacity and vessel size depend upon specific cell culture process conditions.
XCell ATF® Single-use Devices
XCell ATF® 1 Single-use Device
XCell ATF® 2 Single-use Device
XCell ATF® 6 Single-use Device
XCell ATF® 10 Single-use Device
XCell ATF® Single-use Tubing Sets
Filter Wetting Procedure
XCell ATF® Single-use Devices are supplied dry. To ensure robust filter performance, it is important to wet the filter prior to use. The XCell ATF® Tubing Set and the suggested wetting protocols are designed to:
- Ensure efficient and complete filter wetting by minimizing the formation of air pockets during the wetting process
- Enable pre-use filter integrity testing while maintaining sterility
- Provide a means for evaluating the sterility of the XCell ATF® device prior to establishing the bioreactor connection
- Allow change-out of the XCell ATF® device during a cell culture run without interrupting the bioreactor or XCell ATF® operation
XCell ATF® Stainless Steel Devices
XCell ATF® 2 Stainless Steel Device
XCell ATF® 4 Stainless Steel Device
XCell ATF® 6 Stainless Steel Device
XCell ATF® 10 Stainless Steel Device
How to Install a Hollow Fiber Filter
Watch the video on how to install a hollow fiber filter into an XCell ATF® 10 stainless steel device.
XCell™ Controller
XCell™ Lab Controller
for use with:
XCell ATF® 1 (SU)
XCell ATF® 2 (SU,SS)
XCell® ATF 4 (SS)
XCell ATF® C410 Controller
for use with:
XCell ATF® 4 (SS)
XCell ATF® 6 (SU, SS)
XCell ATF® 10 (SU, SS)
XCell ATF® C410 Controller Cart
(optional)
XCell ATF® devices by scale
Resources
Investigation of XCell ATF® Perfusion Technology for virus manufacturing process intensification at MSD Animal Health
Repligen Corporation
MSD Animal Health
July 2022
