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OPUS® Pre-packed Columns
Process Development

OPUS® Columns, formerly Atoll columns, are designed for use in downstream automated parallel chromatography, bench-scale resin screening, process development, and sample preparation.

OPUS® RoboColumn®

Used in the industry since 2007, OPUS® RoboColumns® are miniaturized pre-packed columns on a 96-well plate.  They are designed for efficient automated chromatography process development, resin and sample screening, and sample preparation using robotic liquid handling workstations.

 

OPUS® RoboColumn®

OPUS® MiniChrom™

Designed for bench-scale process development,  OPUS® MiniChrom™ Columns are pre-packed with user-specified resin and supplied ready to use with any liquid chromatography system. Currently platformed in various process development projects, as well as for resin sampling by various resin vendors, over 30,000 OPUS® MiniChrom™ Columns have been in used in the industry since 2005.

OPUS® MiniChrom™

OPUS® CentriColumn™

Designed for centrifuge parallel handling, the OPUS® CentriColumn™ is ideal for high throughput sample preparation.  Up to 96 columns (8 columns in parallel) can be individually arranged on a 96-well array plate according to application requirements. 

  • Pre-packed with user-specified chromatography resin
  • Compatible with any 96 DIN centrifuge able to accept the 41 mm high OPUS® CentriColumn™ array, excluding the base collection plate.

Minimum order is one row of 8 columns with the same resin and column dimensions.

see resin list

Available formats

     
Internal
Diameter		 Bed
Height		 Column Volume 
cm mm cm   mm mL  
0.5 5.0 0.25 2.5 0.05  
0.5 5.0 0.50 5.0 0.10  
0.5 5.0 1.00 10.0 0.20  

OPUS® PIpetColumn™

Designed for use with pipettes, the OPUS® PipetColumn™ is ideal for manual process development with lower volume applications and screening, prior to working with fully automated OPUS® RoboColumn®.

The OPUS® PipetColumn™ is operated with positive liquid displacement pipettes (PLD) such as Eppendorf Multipette® Stream or Xstream.  Up to 96 columns (8 columns in parallel) can be individually arranged on a 96-well array plate according to application requirements. A Starter Kit is also available, made up of one row of 8 OPUS® PipetColumns™.

  • Pre-packed with user-specified chromatography resin
  • Real chromatography mode of operation allows for dynamic vector static chromatography
  • Controlled flow rate by dispensing speed of the used PLD pipette
  • Inexpensive and quick manual process development

See resin list

Available formats

         
Internal
Diameter		 Bed
Height		 Column Volume  Resin  
cm mm cm   mm mL    
0.5 5.0 0.25 2.5 0.05 AIEX  
0.5 5.0 0.50 5.0 0.10 CIEX  
0.5 5.0 1.00 10.0 0.20 HIC Starter Kit
0.5 5.0 2.25 22.5 0.45 IMAC  
0.5 5.0 2.50 25.0 0.50 Protein A  
0.5 5.0 3.00 30.0 0.60 HA  
Starter Kit