Solutions for COVID-19 Therapeutics, Vaccines
Repligen is ready to partner to help fast-track the development and manufacturing of your COVID-19 therapeutics, vaccines and diagnostics.
Use our COVID-19 Hotline for accelerated product availability or expert support.
Repligen IS A technology leader in therapeutics production
Rapid response with COVID-19 accelerated lead times
Proven technologies with broad customer base from clinical to commercial = reduced risk
Adoption in diverse platforms including mAbs, proteins, viruses, plasmids, AAV, Lentivirus, mRNA
Providing high impact solutions with priority support
Expert-guided priority support for rapid technology implementation
Leading technologies for upstream process intensification, downstream processing, process analytics - scalable from bench to production scale
Closed, single-use bioprocessing — single-use, Gamma-irradiated, fully integrated flow paths
Repligen and Navigo Proteins develop affinity ligand for the purification of COVID-19 vaccines
A successful development of an affinity ligand targeting the spike protein, to be utilized in the purification of COVID-19 vaccines, has entered stage two. The program is focused on both scaling up the manufacturing of this ligand, and on the development and validation of the related affinity chromatography resin.
High-Impact solutions for Covid-19 programs
Upstream Solutions
ProConnex® Flow Paths for Install-and-Go TFF
Configurable, sterile assemblies
Reduced installation time
Downstream Solutions
OPUS® 5-80R Columns
with Purolite Pro A Resin
High capacity rPA affinity resin
at a fraction of the cost
ProConnex® Flow Paths
for Install-and-Go TFF
Configurable, sterile assemblies
Reduced installation time
Time-saving, cost-lowering Solutions
Needs and Challenges
- Low shear filtration for pDNA and mRNA purification
- Closed single-use systems, automated and standardized platforms
- Demand for manufacturing can be significant so facility thoughput important
Downstream solutions
Needs and Challenges
- High demand biologic - productivity, efficiency, throughput and process economics need to be considered
- Closed single-use, automated and standardized TFF platforms
- Scalable chromatography and filtration solutions
Upstream solutions
Combines centrifugation and primary depth filtration, scalable from 1 to 2000L
Downstream solutions
Needs and Challenges
- High demand biologic - productivity, efficiency, throughput and process economics need to be considered
- Closed single-use, low shear, automated and standardized TFF platforms
- Scalable chromatography and filtration solutions
Upstream solutions
Combines centrifugation and primary depth filtration, scalable from 1 to 2000L
Downstream solutions
- High demand biologic - productivity, efficiency, throughput and process economics need to be considered
- Closed single-use, low shear, automated and standardized TFF platforms
- Scalable chromatography and filtration solutions
Upstream solutions
Combines centrifugation and primary depth filtration, scalable from 1 to 2000L
Downstream solutions
OPUS® Columns with Purolite Protein A Resin
High capacity rPA affinity resin at a fraction of the cost
Spectrum® Hollow Fiber TFF Filters
Low shear TFF,
1400 configurations
Closed, Gamma-irradiated, no cleaning validation
priority Support available remotely or in person
