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Solutions for COVID-19 Therapeutics, Vaccines
and Diagnostics


Repligen is ready to partner to help fast-track the development and manufacturing of your COVID-19 therapeutics, vaccines and diagnostics.

Use our COVID-19 Hotline for accelerated product availability or expert support.

Repligen IS A technology leader in therapeutics production

Rapid response with COVID-19 accelerated lead times

Proven technologies with broad customer base from clinical to commercial = reduced risk

Adoption in diverse platforms including mAbs, proteins, viruses, plasmids, AAV, Lentivirus, mRNA

Providing high impact solutions with priority support

Expert-guided priority support for rapid technology implementation

Leading technologies for upstream process intensification, downstream processing, process analytics - scalable from bench to production scale

Closed, single-use bioprocessing — single-use, Gamma-irradiated, fully integrated flow paths 

up to 50% faster lead times for Covid-19 programs 

 Corona Virus 3D.png= Currently used in COVID-19 processes

Upstream Solutions

Downstream Solutions

Time-saving, cost-lowering Solutions

Expand All

Needs and Challenges

  • Low shear filtration for pDNA and mRNA purification
  • Closed single-use systems, automated and standardized platforms
  • Demand for manufacturing can be significant so facility thoughput important

Downstream solutions

OPUS® Pre-packed Columns

Ready-to-use, no packing expertise needed

Spectrum® Hollow Fiber TFF Filters

Low shear TFF,
1400 configurations

SIUS® Gamma
TFF Cassettes

Closed, Gamma-irradiated, no cleaning validation

ProConnex®
Flow Paths

Configurable, sterile assemblies, reduced intallation time

KrosFlo®
TFF Systems

Fully automated, scalable from bench to production

SoloVPE®
Analytics

No dilution protein quantitation

Needs and Challenges

  • High demand biologic - productivity, efficiency, throughput and process economics need to be considered
  • Closed single-use, automated and standardized TFF platforms
  • Scalable chromatography and filtration solutions

Upstream solutions

XCell ATF®
Systems

Higher pre-transfection viable cell density and total capsid titer

LONG®R3 IGF-I Growth Factor

200x more potent than insulin

KrosFlo® TFDF® Systems

Combines centrifugation and primary depth filtration, scalable from 1 to 2000L

Downstream solutions

OPUS® Pre-packed Columns

Ready-to-use, no packing expertise needed

Spectrum® Hollow Fiber TFF Filters

Low shear TFF,
1400 configurations

SIUS® Gamma
TFF Cassettes

Closed, Gamma-irradiated, no cleaning validation

https://www.repligen.com/technologies/pro-connex-flowpaths

ProConnex®
Flow Paths

Configurable, sterile assemblies, reduced intallation time

KrosFlo®
TFF Systems

Fully automated, scalable from bench to production

SoloVPE®
Analytics

No dilution protein quantitation

Needs and Challenges

  • High demand biologic - productivity, efficiency, throughput and process economics need to be considered
  • Closed single-use, low shear, automated and standardized TFF platforms
  • Scalable chromatography and filtration solutions

Upstream solutions

Higher pre-transfection viable cell density and total capsid titer

200x more potent than insulin

KrosFlo® TFDF® Systems

Combines centrifugation and primary depth filtration, scalable from 1 to 2000L

Downstream solutions

Ready-to-use, no packing expertise needed

Low shear TFF,
1400 configurations

SIUS® Gamma
TFF Cassettes

Closed, Gamma-irradiated, no cleaning validation

ProConnex®
Flow Paths

Configurable, sterile assemblies, reduced intallation time

KrosFlo®
TFF Systems

Fully automated, scalable from bench to production

SoloVPE®
Analytics

No dilution protein quantitation

  • High demand biologic - productivity, efficiency, throughput and process economics need to be considered
  • Closed single-use, low shear, automated and standardized TFF platforms
  • Scalable chromatography and filtration solutions

Upstream solutions

XCell ATF®
Systems

Higher pre-transfection viable cell density and total capsid titer

LONG®R3 IGF-I Growth Factor

200x more potent than insulin

KrosFlo® TFDF® Systems

Combines centrifugation and primary depth filtration, scalable from 1 to 2000L

Downstream solutions

OPUS® Pre-packed Columns

Ready-to-use, no packing expertise needed

OPUS® Columns with Purolite Protein A Resin

High capacity rPA affinity resin at a fraction of the cost

Spectrum® Hollow Fiber TFF Filters

Low shear TFF,
1400 configurations

SIUS® Gamma
TFF Cassettes

Closed, Gamma-irradiated, no cleaning validation

ProConnex®
Flow Paths

Configurable, sterile assemblies, reduced intallation time

KrosFlo®
TFF Systems

Fully automated, scalable from bench to production

SoloVPE®
Analytics

No dilution protein quantitation

priority Support available remotely or in person

covid-support.png