Spectrum® Hollow Fiber Filter Modules

Ideal for ultrafiltration, diafiltration and microfiltration, single-use hollow fiber filters for tangential flow filtration are packed in housings engineered to handle high pressures, with a choice of fiber chemistries and sizes from process development to manufacturing.

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Spectrum® Hollow Fiber Filter Modules

Hollow fiber filter modules for tangential flow filtration (TFF) from Repligen are industry standards in the filtration and concentration of biologics. Manufactured in compliance with ISO guidelines, the filters are used in thousands of Krosflo TFF Systems and XCell™ ATF Systems worldwide, as well as other industry hollow fiber TFF systems.

Scale-up made easy

Hollow fiber filter TFF modules are offered with a broad range of sizes, surface areas and membrane chemistries designed to facilitate easy scale-up from small volume process development and R&D applications to commercial production. During scale-up, adding more fibers to process larger volumes enables consistency in the length of the filtration flow path even while the surface area of the filter is increased.

	Primary Application	Volume	Inlet/ Outlet	Side Port	Scale Length	Effective Length (cm)	Total Length (cm)	Surface area
MicroKros
Buy Now	Process characterization, Small-volume TFF in a laboratory	1-100 ml	MLL	FLL	1 x FL 2 x FL 3 x FL	20 41.5 65	25 45 69	13 – 20 cm² 26 - 59 cm² 41 - 92 cm²
MidiKros
Buy Now	Process development at small scale	100 ml - 3 L	FLL	FLL	1 x FL 2 x FL 3 x FL	20 41.5 65	25 45 69	75 – 190 cm² 155 - 390 cm² 245 - 610 cm²
MidiKros TC
Buy Now	Process development at pilot scale	100 ml - 3 L	1/2" TC	FLL	1 x FL 2 x FL 3 x FL	20 41.5 65	25 45 69	75 – 190 cm² 155 - 390 cm² 245 - 610 cm²
MiniKros Sampler
Buy Now	Batch TFF of small volumes	3 L -15 L	0.75" TC	0.75" TC	1 x FL 2 x FL 3 x FL	20 41.5 65	25 47 70	490 – 1000 cm² 1000 - 2200 cm² 1600 - 3400 cm²
MiniKros
Request a Quote	Pilot-scale TFF	5 L - 50 L	1.5" TC	0.75" TC	1 x FL 2 x FL 3 x FL	20 41.5 65	25 46 70	0.16 - 0.31 m² 0.32 - 0.65 m² 0.51 - 1.0 m²
KrosFlo^®
Request a Quote	Production-scale TFF	10 – 100L	3" TC	1.5" TC	1 x FL 2 x FL 3 x FL	20 41.5 65	23 46 69	0.78 - 1.6 m² 1.65 - 3.25 m² 2.55 - 5.10 m²
KrosFlo^® MAX
Request a Quote	Production-scale TFF	100L – 1000+L	6" TC	1.5" TC	R65 3 x FL R85	49.9 67.9 107.5	73.5 91.5 131.1	4.30 - 10.40 m² 7.10 - 17.10 m² 11.30 - 11.35 m²

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Repligen develops and manufactures products for the biopharmaceutical industry under an ISO 9001 quality management system. We focus on the timely delivery of high quality, consistent and robust products, to ensure business continuity for our customers.

Repligen manufacturing sites are located in Massachusetts, California, and New Jersey in the United States and in Sweden, France, The Netherlands, Germany and Estonia.

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