Spectrum® Hollow Fiber Filter Modules
Ideal for ultrafiltration, diafiltration and microfiltration, single-use hollow fiber filters for tangential flow filtration are packed in housings engineered to handle high pressures, with a choice of fiber chemistries and sizes from process development to manufacturing.
Spectrum® Hollow Fiber Filter Modules
Hollow fiber filter modules for tangential flow filtration (TFF) from Repligen are industry standards in the filtration and concentration of biologics. Manufactured in compliance with ISO guidelines, the filters are used in thousands of Krosflo TFF Systems and XCell™ ATF Systems worldwide, as well as other industry hollow fiber TFF systems.
Scale-up made easy
Hollow fiber filter TFF modules are offered with a broad range of sizes, surface areas and membrane chemistries designed to facilitate easy scale-up from small volume process development and R&D applications to commercial production. During scale-up, adding more fibers to process larger volumes enables consistency in the length of the filtration flow path even while the surface area of the filter is increased.
| Primary Application | Volume | Inlet/ Outlet | Side Port | Scale Length | Effective Length (cm) | Total Length (cm) | Surface area | |
|---|---|---|---|---|---|---|---|---|
MicroKros |
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Process characterization, Small-volume TFF in a laboratory | 1-100 ml | MLL | FLL | 1 x FL 2 x FL 3 x FL |
20 41.5 65 |
25 45 69 |
13 – 20 cm2 26 - 59 cm2 41 - 92 cm2 |
MidiKros |
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Process development at small scale | 100 ml - 3 L | FLL | FLL | 1 x FL 2 x FL 3 x FL |
20 41.5 65 |
25 45 69 |
75 – 190 cm2 155 - 390 cm2 245 - 610 cm2 |
MidiKros TC |
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Process development at pilot scale | 100 ml - 3 L | 1/2" TC | FLL | 1 x FL 2 x FL 3 x FL |
20 41.5 65 |
25 45 69 |
75 – 190 cm2 155 - 390 cm2 245 - 610 cm2 |
MiniKros Sampler |
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Batch TFF of small volumes | 3 L -15 L | 0.75" TC | 0.75" TC | 1 x FL 2 x FL 3 x FL |
20 41.5 65 |
25 47 70 |
490 – 1000 cm2 1000 - 2200 cm2 1600 - 3400 cm2 |
MiniKros |
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Pilot-scale TFF | 5 L - 50 L | 1.5" TC | 0.75" TC | 1 x FL 2 x FL 3 x FL |
20 41.5 65 |
25 46 70 |
0.16 - 0.31 m2 0.32 - 0.65 m2 0.51 - 1.0 m2 |
KrosFlo® |
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Production-scale TFF | 10 – 100L | 3" TC | 1.5" TC | 1 x FL 2 x FL 3 x FL |
20 41.5 65 |
23 46 69 |
0.78 - 1.6 m2 1.65 - 3.25 m2 2.55 - 5.10 m2 |
KrosFlo® MAX |
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 Request a Quote |
Production-scale TFF | 100L – 1000+L | 6" TC | 1.5" TC | R65 3 x FL R85 |
49.9 67.9 107.5 |
73.5 91.5 131.1 |
4.30 - 10.40 m2 7.10 - 17.10 m2 11.30 - 11.35 m2 |
Find the right Hollow Fiber Filter for your application
Product Number Key
To specify the hollow fiber filter specific to your application, follow the product number key below.
Manufacturing Centers of Excellence
Repligen develops and manufactures products for the biopharmaceutical industry under an ISO 9001 quality management system. We focus on the timely delivery of high quality, consistent and robust products, to ensure business continuity for our customers.
Repligen manufacturing sites are located in Massachusetts, California, and New Jersey in the United States and in Sweden, France, The Netherlands, Germany and Estonia.
Customer First.
Support is part of the Repligen DNA. Our goal is to provide exceptional customer experience, and to support the efficient and successful adoption and implementation of all Repligen products and services.
- Field Application Support
- Customer Service
- Field Service Engineers
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