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SpectraPor® Biotech Grade Cellulose Ester (CE) Dialysis Membrane

Repligen produces molecular porous Biotech Grade Cellulose Ester (CE) membranes in a large range of MWCO’s specifically for critical MW separations using a proprietary casting process free of heavy metal and sulfur contaminants.  The CE dialysis tubing is ultra-pure and does not require special cleaning or treatment.

Biotech CELLULOSE Ester (CE) Dialysis Tubing and Kits

Biologically inert and ultra-pure, SpectraPor® Biotech CE Dialysis Membrane provides superior molecular selectivity and is available in the largest selection of 9 concise MWCO's ranging from 0.1 – 1,000 kD, whether purifying small MW solutes or isolating large macromolecules or nanoparticles.  Biotech CE membrane generally tolerates weak or dilute acids & bases and mild alcohols and is compatible with pH 2-9 and temp 4-37 °C. Exposure to most organic solvents is not recommended and should be confirmed on the Repligen Chemical Compatibility table.

Simply soak and rinse in DI water, apply Universal Tubing Closures and load sample.

FEATURES & BENEFITS

  • High purity for critical and GMP dialysis - no heavy metals or sulfides
  • Rigidly controlled porosity for better selectivity & separations
  • No interference with macromolecular activity & function
  • No glycerin removal and no pretreatment required
  • Available in rolled tubing for economy and trial kits for evaluation

Typical Dialysis Applications for Biotech CE

  • Salt removal and HPLC sample preparation
  • pH change, buffer exchange and final formulation
  • Purification of Protein, DNA, plasmids, macromolecules, nanoparticles and liposomes
  • Polymer synthesis and isolation (polypeptide, oligonucleotide, polysaccharide)
  • Biopolymer and hydrogel purification (hyaluronic acid, collagen, chitosan)
  • Large volume and GMP batch process dialysis
  • Enzyme activity and ligand binding studies
  • Drug dissolution and controlled release studies
  • DNA and Protein electroelution

Product Specifications

   
Properties: Mildly hydrophobic, symmetric porosity
9 MWCO's: 0.1-0.5 kD, 0.5-1.0 kD, 3.5-5 kD, 8-10 kD, 20 kD, 50 kD, 100 kD, 300 kD, 1000 kD
4 Flat Widths: 100 mm, 16 mm, 24 mm, 31 mm
Quantity & Packaging:  Wet in 0.05% sodium azide, 10 m/roll or 1 m/trial kit (includes 2 closures) 

Part Numbers

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MWCO

(kD)

Flat Width

(mm)

Diameter

(mm)

Vol/Length

(ml/cm)

Part No.

 0.1 - 0.5

10

16

24

31

6.4

10

15

20

0.32

0.79

1.8

3.1

131048

131054

131057

131060

         

0.5 - 1.0

10

16

24

31

6.4

10

15

20

0.32

0.79

1.8

3.1

131084

131090

131093

131096

         

3.5 - 5

10

16

24

31

6.4

10

15

20

0.32

0.79

1.8

3.1

131192

131198

131201

131204

         

8 - 10

10

16

24

31

6.4

10

15

20

0.32

0.79

1.8

3.1

131264

131270

131273

131276

         

20

10

16

24

31

6.4

10

15

20

0.32

0.79

1.8

3.1

131336

131342

131345

131348

         

50

10

16

24

31

6.4

10

15

20

0.32

0.79

1.8

3.1

131372

131378

131381

131384

         

100

10

16

24

31

6.4

10

15

20

0.32

0.79

1.8

3.1

131408

131414

131417

131420

         

300

16

31

10

20

0.79

3.1

131450

131456

         

1000

16

31

10

20

0.79

3.1

131486

131492

MWCO

(kD)

Flat Width

(mm)

Diameter

(mm)

Vol/Length

(ml/cm)

Part No.

 0.1 - 0.5

10

16

24

31

6.4

10

15

20

0.32

0.79

1.8

3.1

131048T

131054T

131057T

131060T

         

0.5 - 1.0

10

16

24

31

6.4

10

15

20

0.32

0.79

1.8

3.1

131084T

131090T

131093T

131096T

         

3.5 - 5

10

16

24

31

6.4

10

15

20

0.32

0.79

1.8

3.1

131192T

131198T

131201T

131204T

         

8 - 10

10

16

24

31

6.4

10

15

20

0.32

0.79

1.8

3.1

131264T

131270T

131273T

131276T

         

20

10

16

24

31

6.4

10

15

20

0.32

0.79

1.8

3.1

131336T

131342T

131345T

131348T

         

50

10

16

24

31

6.4

10

15

20

0.32

0.79

1.8

3.1

131372T

131378T

131381T

131384T

         

100

10

16

24

31

6.4

10

15

20

0.32

0.79

1.8

3.1

131408T

131414T

131417T

131420T

         

300

16

31

10

20

0.79

3.1

131450T

131456T

         

1000

16

31

10

20

0.79

3.1

131486T

131492T

Resources

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