TangenX® SIUS® Cassettes are the first purpose-built single-use cassettes for tangential flow filtration (TFF). They deliver equivalent performance as reusable cassettes but with single-use convenience and at a fraction of the cost.
TangenX® PRO Reusable Tangential Flow Filtration (TFF) Cassettes are flat sheet cassettes that may be cleaned and re-used multiple times while maintaining reproducible cassette performance. They are engineered with optimized channel geometry and enhanced device rigidity to ensure that hydraulic performance is maintained during processing and scale-up.
TangenX® SIUS® Gamma TFF Devices embody the performance and efficiency of TangenX® SIUS® Cassettes in a convenient, fully assembled, closed, and irradiated system.
Simply clamp your TangenX® SIUS® Gamma TFF Device into a holder, connect to a flow path, and go. It's that easy.
Acclaimed performance with up to 30% flux increase over conventional membranes, connectivity freedom, and a library of configurations, converge into one, simple TFF solution.
Use TangenX® SIUS® Gamma TFF Devices for gene therapy applications, bioburden-sensitive operations, and hazardous processes.
Repligen manufactures two flat sheet TFF membranes: ProStream™ and HyStream™. Both are modified Polyethersulfone (mPES) membranes validated for use in cGMP processes. Both ProStream and HyStream membranes are available in TangenX® SIUS® Single-use Cassettes and TangenX® PRO Reusable Cassettes.
Designed to optimize tangential flow filtration, TangenX® hardware include: