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Fluid Management

Fluid management is critical in upstream and downstream biopharmaceutical manufacturing processes. Each fluid transfer and storage component, regardless of size, presents a risk of failure as well as an opportunity for step advances in process economics and process efficiency.

Single-use Flow Paths

Customized, configurable and complete ProConnex® flow paths optimize the connectivity of TFF, TFDF and/or chromatography systems to the workflow. General use flow paths are designed according to specific customer specifications for a specific customer application.

proconnex® flow paths

fluid management components

Single-use components

Designed-for-purpose transfer and containment assemblies feature state-of-the-art overmolding technology that help optimize fluid transfer, reduce number of connections and do not use leak-prone fasteners.

molded components and tubing

bottles and containers

Process equipment

Configured to precise customer specifications, Repligen durable consumables are made of extremely chemical-resistant non-metallic materials that eliminate the use of stainless steel, with zero corrosion or pitting. 

Totes, Carts, Tanks

Organizers, Cleanroom equipment

Single-use valves 

Innovative valve technology enables automated flow control. Configurable, modular flexibility is built-in  with no additional cleaning, sterilization and validation steps required.

Diaphragm Replacement valves

Pinch valves

Steam2® Sample valves

Manufacturing excellence

Repligen develops and manufactures products for the biopharmaceutical industry under an ISO 9001 quality management system.  We focus on the timely delivery of high quality, consistent and robust products, to ensure business continuity for our customers.

about repligen manufacturing

Fluid management molded components and tubing are designed and manufactured by Engineered Molding Technology (EMT), a Repligen Company, experts in state-of-the-art liquid injection molded silicone techniques.  Since 2010, EMT specializes in the manufacture of silicone custom-molded shapes and stand-alone molded parts for biopharmaceutical applications. Located in a 20,000 square foot facility in Clifton Park, New York, EMT uses ISO 7-certified (Class 10,000) clean rooms for all production and packaging and follows a comprehensive ISO compliant quality system with full traceability of all components.

Fluid management single-use bottles and containers are designed and manufactured by NMS Bioproduction (NMS), a Repligen Company.  NMS specializes in plastic fabrication, standard thermoplastic tanks, as well as rotational molding (rotomolding) expertise. Located in Millbury, Massachusetts, NMS is ISO13485:2016 certified and has been providing custom non-metallic solutions to the biopharmaceutical, pharmaceutical and medical markets since August 2006.