Applications in this therapeutic class include the bioprocessing of
• Exosomes
• Nanoparticles
• Polysaccharides
Macro Molecule Process flow and Applications
Cell culture ►
Expansion of host cell
Cell line optimization
Cell banking
Media development
Seed train optimization
Cell Culture process development
Analytics
Applications
N-1 Perfusion
Media Exchange
Repligen solutions
Infection ►
(if relevant)
Harvest ►
Centrifugation
Depth filtration (may be multi-stage)
Analytics
Purification ►
Resin screening
Capture / Polish chromatography
Scale-down validation
Tangential flow filtration
Analytics
Applications
Pre-packed column
UF/DF
Repligen solutions
Formulation ►
Filter screening
Tangential flow filtration
Analytics
Applications
Concentration and Diafiltration
Repligen solutions
Fill/Finish
Analytics
Applications
Concentration/lot release
Repligen Solutions