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Repligen Reports Fourth Quarter and Full Year 2019 Financial Results
Reports quarterly revenue of $69.5 million, representing 34% year-over-year growth, and annual revenue of $270.2 million represents 39% year-over-year growth Overall organic revenue growth was 21% for the fourth quarter and 33% for the year 2019 WALTHAM, Mass., Feb. 20, 2020 (GLOBE NEWSWIRE) - Repligen Corporation (NASDAQ:RGEN), a life sciences company focused on bioprocessing technology leadership, today reported financial results for its fourth quarter and full year 2019. Provided in this press release are financial highlights for the three - and twelve-month periods ended December 31, 2019, followed by our current financial guidance for the year 2020, and access information for today’s webcast and conference call. Tony J. Hunt, President and Chief Executive Officer said, “We are delighted with the way we finished off 2019 with 21% organic growth in the fourth quarter and 33% for the full year. Our Filtration and Chromatography franchises accelerated in 2019 as we expanded our
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Repligen Reports First Quarter 2018 Financial Results
Record quarterly revenue of $44.8M represents 46% year-over-year growth Revenue guidance raised to $182-$188 million for full year 2018 WALTHAM, Mass., May 08, 2018 (GLOBE NEWSWIRE) - Repligen Corporation (NASDAQ:RGEN), a life sciences company focused on bioprocessing technology leadership, today reported financial results for its first quarter ended March 31, 2018. Provided in this press release are financial highlights for the quarter, updates to our financial guidance for the year 2018 and access information for today's webcast and conference call. Tony J. Hunt, President and Chief Executive Officer said, “We had a strong start to the year led by sales of our direct filtration and chromatography products, which were up by over 90% year-on-year. This includes our Spectrum business, which continues to outperform our expectations. We are also excited about the depth of our R&D pipeline which is generating new products, including our recently launched OPUS 80R pre-packed columns
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High Productivity Harvest
High Productivity Harvest (HPH) is a novel application developed by Repligen that enables the harvest of a Fed-Batch bioreactor in a fully sterile manner ready for processing on a capture column, eliminating both centrifugation and depth filtration.
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Accelerating analytical testing for GMP plasmid production
The challenges associated with gene therapy bioprocessing are numerous and burdensome, from scalability to Cost of Goods control, and from ensuring quality/consistency to accessing sufficient capacity and expertise. The consensus of opinion in the field is that a largely or fully automated process based upon a single, easy-to-use platform would be optimal, as would the adoption of single-use technology. The majority of challenges that arise with testing of gene therapy materials relate to time and accuracy. The CTech™ SoloVPE® and FlowVPX® slope spectroscopy technology is specifically designed to address these very issues Speaker: Paul Mania
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Drug-to-Antibody Ratio
Challenge: DAR is a critical quality attribute for ADCs, but offline methods are often low-throughput. Our Solution: FlowVPX enables in-line DAR monitoring for consistency and compliance during conjugation.
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Introducing the KrosFlo® KR2i RPM™ System
Monitor concentration during your UF/DF run with the new KrosFlo KR2i RPM System. Featuring in-line protein concentration management, you control your process with the power of the KrosFlo KR2i TFF System and insights from the CTech™ FlowVPX® System.
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Protein Concentration (A280)
Challenge: Manual concentration checks introduce variability and slow down release timelines. Our Solution: FlowVPX and SoloVPE PLUS offer rapid, dilution-free quantification at every stage—from UF/DF to final fill.
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Metabolomics
Challenge: Understanding cellular metabolism is essential, but metabolite shifts are transient and easily missed in offline workflows. Our Solution: With REBEL XT, real-time monitoring of nutrient consumption and byproduct accumulation drives smarter decisions on feed timing and culture viability.
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Model Predictive Control for automated biologics drug product manufacturing (Janssen)
This presentation focuses on the development, testing, and justification of an advanced control strategy for automating the dilution process during the formulation step in fill-finish manufacturing. The proposed control strategy is founded on precise, accurate and fast protein concentration measurements, all provided by the FlowVPE technology. Being able to rely on timely, high-quality concentration measurements, the novel strategy combines the FlowVPE implemented on-line with real-time data processing and modelling, to achieve immediate feedback control of the dilution process without the need for human intervention.   Speakers: Janssen-Renata Pocitarenco, JSC Process Modelling and Marius Mueller, DPDS Analytical Development – Janssen.
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Manual TFF lab scale chaos to controlled success
Not all TFF systems are created equal. Turn the chaos of manually adjusting flowrates, monitoring pressures and documenting data every 10 minutes into automated TMP control and data recording. During this webinar we’ll discuss how the KrosFlo® KR2i, KMPi, and FS family of systems solve challenges of human error, reproducibility, and scalability with economical, easy-to-use lab scale TFF systems with automation capabilities.
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