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Tulip-tank-case-study
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Innovative, differentiated technologies advancing new modalities: Case studies in mRNA & viral vectors
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Optimizing E. Coli cell growth performance with in-line, real-time OD600 (abs/mm) monitoring during the fermentation process
This study proposes utilizing an inline- variable pathlength spectrophotometer in a recirculation loop during fermentation to monitor and optimize the growth of E. Coli cells in real-time. This provides distinct advantages vs traditional methods due to the constant modification of path lengths to create a slope-based solution that is always within the linear range of the equipment with no buffer correction required. The growth curve is tracked in real-time using the slope (Absorbance/mm) at 600nm to measure cell density and to optimize growth performance of E. Coli cells. This will serve as a proof-of-concept for the optimal cultivation of E. Coli and production of pDNA. Speakers: Tanja Buch, Ramsey Shanbaky
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SpectraPor® Tubing Closures
Available in three functional types, SpectraPor® Tubing Closures are intended for use with Regenerated Cellulose (RC) dialysis tubing to ensure a leak-proof seal. These closures are not recommended for use with Cellulose Ester (CE).
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Proven Process Intensification Strategies for Upstream Bioprocessing
These technical white papers discuss economic modeling and real-world case studies of N-stage and N-1 upstream process intensification using perfusion with XCell® ATF technology to reduce COGs, increase space-time yield, and unlock ROI.
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Ligands
Leader in Protein A ligand manufacturing since 1985. Most of the world's commercial monoclonal antibodies are purified using native and recombinant Protein A ligands manufactured by Repligen.
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Downstream Filtration | Bioprocessing
Downstream filtration in bioprocessing aims to remove unwanted substances (such as cell debris, viruses and bacteria) from cell media and other downstream processes, to filter out the Active Pharmaceutical Ingredients (API).  
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DOC0452 App Note - Rapid characterization of oligonucleotides using microfluidic capillary electrophoresis-mass spectrometry by the PATsmart ZipChip System
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Cell Culture
Cell culture, or cell expansion, refers to upstream methods that enable the growth of eukaryotic or prokaryotic cells in physiological conditions, for subsequent downstream purification and filtration.
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PATsmart™ Consumable Products - PATsmart™ Analytical Solutions
Purchase the essential instruments and consumable products to power your PATsmart™ Variable Pathlength Technology.
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