Logout Login Cart iconShop
Contact Sales

Search

Filters

Content Type

Products

Clear Filters

Search Results for "certificate of analysis/1000"

Looking for quality documents?
corporate icon
High Productivity Harvest
High Productivity Harvest (HPH) is a novel application developed by Repligen that enables the harvest of a Fed-Batch bioreactor in a fully sterile manner ready for processing on a capture column, eliminating both centrifugation and depth filtration.
corporate icon
ATMP
Advanced Therapy Medical Products (ATMP) have immense potential to transform the lives of patients with genetic diseases. Repligen partners with developers and manufacturers, providing technology breakthroughs and high impact solutions for plasmid and viral vector development and manufacturing.
video icon
Evaluating the new CTech FlowVPX System for UF/DF-Protein Concentration (Bristol-Myers Squibb)
An evaluation of a beta version of the FlowVPX and Viper software was performed to determine it’s potential as an inline instrument for product concentration measurement during UF/DF operation, particularly high concentration UF/DF processes that are required for subcutaneous injection formulations (greater than 150 g/L). The FlowVPX has significant potential for GMP and commercial biologics manufacturing unlike the first generation FlowVPE, which was designed as a lab scale instrument. Extensive testing was done using small and pilot scale UF/DF operations with several biologic drugs molecules from the portfolio. The FlowVPX instrument demonstrated very good comparability with other A280 based protein concentration measurements for all molecules tested (six). From a technical standpoint the FlowVPX is a GMP ready instrument, and further testing for instrument robustness and software development is ongoing at present to potentially use the instrument in the GMP space within the near future. Speaker: Jay West, Ph.D., Principal Scientist Biologics Process Development – BMS.
event icon
Advancing TFF for Small Scale CGMP Production with KrosFlo RS 10
The latest in TFF system innovation by Repligen is here Get an inside look into a new purpose-built single-use TFF system designed for process development and CGMP production of mRNA, gene therapies, and personalized medicine- The KrosFlo RS 10  While much of the equipment that is being leveraged for these applications today are repurposed from applications supporting significantly larger volume ranges, this system truly satisfies the demand for smaller scales. With unique features including complete end-to-end automation and optional real-time concentration measurement, this TFF system may be exactly what you need to produce your next blockbuster drug.
video icon
Model Predictive Control for automated biologics drug product manufacturing (Janssen)
This presentation focuses on the development, testing, and justification of an advanced control strategy for automating the dilution process during the formulation step in fill-finish manufacturing. The proposed control strategy is founded on precise, accurate and fast protein concentration measurements, all provided by the FlowVPE technology. Being able to rely on timely, high-quality concentration measurements, the novel strategy combines the FlowVPE implemented on-line with real-time data processing and modelling, to achieve immediate feedback control of the dilution process without the need for human intervention.   Speakers: Janssen-Renata Pocitarenco, JSC Process Modelling and Marius Mueller, DPDS Analytical Development – Janssen.
news icon
Introducing the KrosFlo® KR2i RPM™ System
Monitor concentration during your UF/DF run with the new KrosFlo KR2i RPM System. Featuring in-line protein concentration management, you control your process with the power of the KrosFlo KR2i TFF System and insights from the CTech™ FlowVPX® System.
corporate icon
Protein Concentration (A280)
Challenge: Manual concentration checks introduce variability and slow down release timelines. Our Solution: FlowVPX and SoloVPE PLUS offer rapid, dilution-free quantification at every stage—from UF/DF to final fill.
Close modal

A new look. A better way to explore Repligen.

We’ve redesigned Repligen.com to help you find the right solutions faster, with greater clarity and less effort.

Find what you need faster
Get to the right information with quicker site speed

Explore the site with ease
Navigate easily with an intuitive, simple site structure

Access product details instantly
Find products and resources faster, in fewer clicks

Get support when you need it
Connect with our team when you need support