Production Scale Pre-packed Chromatography for Use with 1000 L and 2000 L Bioreactors

Production Scale Pre-packed Chromatography for Use with 1000 L and 2000 L Bioreactors

Fletcher Malcom, Director of Product Management, Repligen

Abstract

The technical and economic benefits of ready-to-use, pre packed chromatography columns at bench- and small-scale have been proven and documented. The question remains: how do we scale up to production-scale? Now, for the first time, the new OPUS^® 45 and 60 cm columns can purify a feed stream from a 1000L – 2000L bioreactor. This webinar will show how the unique design of these GMP-scale columns deliver equivalent or better performance as self-packed glass columns, and demonstrate how usage can result in substantial cost and time savings.

Speaker Bio

Fletcher Malcom is a creative MBA graduate and biopharmaceutical industry professional, who spent his early career with Waters Corporation as a technical chromatography representative working with large pharmaceutical and biotechnology clients in the Eastern United States. Since leaving Waters, Fletcher has graduated with honors from Babson’s MBA program, and joined Repligen as a Product and Marketing Manager.  In 2011 & 2012 Fletcher led all efforts to complete the development and commercialization of Repligen’s new platform of OPUS^® pre-packed disposable columns. Currently, Fletcher is the Director of Product Management for Repligen's Downstream Technologies.