ProConnex TFDF Flow Paths

Closed, single-use and complete flow paths optimize TFDF™ (Tangential Flow Depth Filtration) processing with integrated sensors and ready-to-use convenience.

OPTIMIZED FOR TFDF™ processing

The single-use, Gamma-irradiated and closed ProConnex^®TFDF™ Flow Path enables seamless tangential flow depth filtration on a KrosFlo^® TFDF™ System. ProConnex^® TFDF™ Flow Paths arrive dry, free of sodium hydroxide, glycerin, preservative and ethanol, for a zero flush start state. The feed stream enters the bottom port. The retentate travels through the lumen and exits at the top of the tube. The permeate exits the enclosure through the lower permeate port.

ProConnex^® TFDF™ Flow Paths are complete assemblies that include:

TFDF™ Filter
Disposable pump head
Integrated sensors
Tubing
Aseptic connectors

Technology

Systems

how it works

COMPLETE, READY-TO-USE TFDF™ FLOW PATHS

TFDF™ 3 Filter
Surface Area: 3 cm²

ProConnex^®TFDF™
Flow Path
Surface Area: 3 cm²

ProConnex^®TFDF™
Flow Path
Surface Area: 150 cm²

ProConnex^®TFDF™
Flow Path
Surface Area: 1500 cm²

ProConnex^®TFDF™
Flow Path
Surface Area: 6000 cm²

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Optimized for TFDF

Closed, Gamma-irradiated, complete with integrated sensors

Single-use

Ready-to-use convenience

Integrated

For use with KrosFlo^® TFDF™ Systems

Repligen develops and manufactures products for the biopharmaceutical industry under an ISO 9001 quality management system. We focus on the timely delivery of high quality, consistent and robust products, to ensure business continuity for our customers.

about repligen manufacturing

CAPACITY INCREASES WITH TUBE NUMBER AND LENGTH

To ensure linear scalability from 1 to 2000 L, the tube length and the number of tubes per enclosure increases. Tube length increases from 20 cm to 108 cm. The effective length of the filter may be less than the physical length of the filter. The number of tubes increases from 1 - 40 per enclosure.

Number of tubes