Proprietary, menu-driven software optimized for use with KrosFlo® KR2i and KrosFlo® KMPi Tangential Flow Filtration Systems
Still using legacy KF Comm software?
See KF Comm 2 in action.
Menu-driven software for optimized Tangential Flow Filtration
KF Comm2 Software, backward compatible with legacy KrosFlo® KR2i and KrosFlo® KMPi Systems, can be conveniently installed on most computers using the Windows Operating System. The software is compatible with Chrome, Mozilla, Firefox and Microsoft Explorer browsers and is always current with automatic software and firmware updates.
OPTIMIZED FOR KROSFLO® TFF SYSTEMS
Designed for use with KrosFlo® KR2i and KrosFlo® KMPi TFF Systems
Compatible with multiple
web browsers
MAY BE VALIDATED FOR GMP
PROCESSES
21 CFR Part 11 option
Login module with
electronic signature for tracking experiments
Intuitive
workflow
13 modes of operation
Realtime tracking from setup to analysis
Optional 21 CFR Part 11 Compliance
KF Comm 2 software may be validated for GMP processes with optional 21 CFR Part 11 compliance.
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Available for customers that require the system to be validated for GMP processes
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Includes user-specific access control via an administration console
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Login module with electronic signature that logs when the user is running experiments and accessing archived data
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Audit Trail /Auditor role
Proprietary KF Comm 2 Software
KF Comm 2 Software
- Automatically collects process data
- Provides real-time overviews of the filtration process
Microsoft Surface Pro 4
- Automatically graphs data and trends in the software
Real-time operating parameters
- Time
- Feed Pressure
- Retentate Pressure
- Permeate Pressure
- Feed Flow Rate
- Diafiltration Flow Rate
- Permeate Flow Rate
- Feed Scale Weight
- Permeate Scale Weight
- Pump RPM
- Notes (Alarms, Process status, Functions)
- Pump Mode
Processing parameters
- Transmembrane Pressure (TMP)
- Pressure Drop (ΔP)
- Retentate Flow Rate
- Permeate Flux
- Volumetric Throughput (VT)
- Concentration Factor
- Shear
- Diafiltration Volumes
- Process Time
- UV, Conductivity, and Temperature (with KONDUiT)
| Process Control Modes | Primary Application | |
|---|---|---|
| M |
Manual Mode |
Manual operation of pumps and auxiliary components |
| CONT |
Continuous Mode |
Manual operation of pumps and auxiliary components with operator interface step of operation (concentration and diafiltration) |
| C |
Concentration Mode |
Simple concentration of the process solution. Automated flushing of the hollow fiber filter |
| C/D |
Concentration / Diafiltration |
Concentration and then diafiltration of the process solution in succession |
| C/D/C |
Concentration / Diafiltration / Concentration |
Diafiltration of the process solution with one buffer before concentration of the process solution a second time |
| C/D/D/C |
Concentration / Diafiltration / Diafiltration / Concentration |
Diafiltration of the process solution with two different buffers in succession before concentration of the process solution a second time |
| CFC |
Constant Feed Concentration |
Concentration of the solution while maintaining a constant feed weight |
| CF/D/C |
Constant Feed Concentration / Diafiltration / Concentration |
Concentration of the solution while maintaining a constant feed weight, then washing the solution with a buffer during diafiltration, followed by further concentration of the solution |
| V |
*NEW* Control mode (Vacuum Mode) |
Use Constant Feed Mode and/or Diafiltration Mode without the need of auxiliary pumps. The solution is drawn into the Feed reservoir by the vacuum created in the reservoir as the solution permeates out of the filter |
| F |
*NEW* Flushing Mode |
Flush mode |
| NWP |
*NEW* Normalized Water Permeability Mode |
Used to determine filter cleanliness after cleaning and used to determine the water flux of a new module |
| C |
*NEW* Cleaning Mode |
Clean mode |
| FE |
*NEW* Flux Excursion Mode |
Measure flux rate |