You are using an unsupported browser.
Some features of this site may not function properly. For optimal user experience, please view this site in Chrome, Firefox, Safari, or Edge.

KF Comm 2 Software

Proprietary, menu-driven software optimized for use with KrosFlo® KR2i and KrosFlo® KMPi Tangential Flow Filtration Systems

Still using legacy KF Comm software?

Upgrade Now

See KF Comm 2 in action.

Request a demo

Menu-driven software for optimized Tangential Flow Filtration

KF Comm2 Software, backward compatible with legacy KrosFlo® KR2i and KrosFlo® KMPi Systems, can be conveniently installed on most computers using the Windows Operating System. The software is compatible with Chrome, Mozilla, Firefox and Microsoft Explorer browsers and is always current with automatic software and firmware updates. 

OPTIMIZED FOR KROSFLO® TFF SYSTEMS

Designed for use  with KrosFlo® KR2i and KrosFlo® KMPi TFF Systems

Compatible with multiple
web browsers 

MAY BE VALIDATED FOR GMP
PROCESSES

21 CFR Part 11 option

Login module with
electronic signature for tracking experiments

Intuitive
workflow

13 modes of operation

Realtime tracking from setup to analysis

Optional 21 CFR Part 11 Compliance 

KF Comm 2 software may be validated for GMP processes with optional 21 CFR Part 11 compliance.

  • Available for customers that require the system to be validated for GMP processes
  • Includes user-specific access control via an administration console 
  • Login module with electronic signature that logs when the user is running experiments and accessing archived data
  • Audit Trail /Auditor role
     

Menu-driven workflow from setup to analysis

Setup
START
Monitor
Review

Proprietary KF Comm 2 Software

KF Comm 2 Software

  • Automatically collects process data
  • Provides real-time overviews of the filtration process

Microsoft Surface Pro 4

  • Automatically graphs data and trends in the software

Real-time operating parameters

  • Time
  • Feed Pressure
  • Retentate Pressure
  • Permeate Pressure
  • Feed Flow Rate
  • Diafiltration Flow Rate
  • Permeate Flow Rate 
  • Feed Scale Weight
  • Permeate Scale Weight
  • Pump RPM
  • Notes (Alarms, Process status, Functions)
  • Pump Mode

Processing parameters

  • Transmembrane Pressure (TMP)
  • Pressure Drop (ΔP)
  • Retentate Flow Rate
  • Permeate Flux
  • Volumetric Throughput (VT)
  • Concentration Factor
  • Shear
  • Diafiltration Volumes
  • Process Time
  • UV, Conductivity, and Temperature (with KONDUiT)
Process Control Modes Primary Application
M

Manual Mode

Manual operation of pumps and auxiliary components

CONT

Continuous Mode

Manual operation of pumps and auxiliary components with operator interface step of operation (concentration and diafiltration)

C

Concentration Mode

Simple concentration of the process solution. Automated flushing of the hollow fiber filter

C/D

Concentration / Diafiltration

Concentration and then diafiltration of the process solution in succession

C/D/C

Concentration / Diafiltration / Concentration

Diafiltration of the process solution with one buffer before concentration of the process solution a second time

C/D/D/C

 Concentration / Diafiltration / Diafiltration / Concentration

Diafiltration of the process solution with two different buffers in succession before concentration of the process solution a second time

CFC

Constant Feed Concentration

Concentration of the solution while maintaining a constant feed weight

CF/D/C

Constant Feed Concentration / Diafiltration / Concentration

Concentration of the solution while maintaining a constant feed weight, then washing the solution with a buffer during diafiltration, followed by further concentration of the solution

V

 *NEW* Control mode (Vacuum Mode)

Use Constant Feed Mode and/or Diafiltration Mode without the need of auxiliary pumps. The solution is drawn into the Feed reservoir by the vacuum created in the reservoir as the solution permeates out of the filter

F

*NEW* Flushing Mode

Flush mode

NWP

*NEW* Normalized Water Permeability Mode

Used to determine filter cleanliness after cleaning and used to determine the water flux of a new module

C

*NEW* Cleaning Mode

Clean mode

FE

*NEW* Flux Excursion Mode

Measure flux rate