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Repligen acquires ARTeSYN Biosolutions and Non-Metallic Solutions (NMS)

Adds gold standard single-use downstream bioprocessing systems and strengthens single-use flow path, durable plastics and assembly portfolio                   



Repligen Solutions From Gene to Therapy

Repligen partners with gene therapy developers and manufacturers, providing technology-ready breakthroughs and high impact solutions for plasmid DNA, AAV and Lentivirus viral vector manufacturing.

Gene Therapy Solutions

Fast-track your covid-19 therapeutics, Vaccines and Diagnostics

ARTeSYN® and Repligen are now one

Together, Repligen and ARTeSYN now provide best-in-class single-use bioprocessing systems and industry-leading filtration and chromatography solutions.

  • Single-use TFF Systems
  • Single-use Viral Filtration Systems
  • Single-use Final Filtration and Bulk Filling Systems
  • Single-use Chromatography Systems


 What's new from Repligen

Introducing TFDF®

tangential flow depth filtration

about_tfdf.jpgNovel High Flux Single-use Filtration for Fed-Batch Clarification

TFDF® (Tangential Flow Depth Filtration) technology unites the benefits of tangential flow (TF) and depth filtration (DF) in a closed and single-use solution that enables 1000 LMH.



Scale Up with OPUS®: OPUS® 80R


OPUS® 80R is the first and only pre-packed column enabling purification of over 10 kilograms of protein in a single cycle.

OPUS® Pre-packed Chromatography Columns offer unparalleled flexibility in media choice, application and size. Applying the most advanced pre-packed chromatography column technology available today, OPUS® columns are ready-to-use alternatives to traditional self-packed columns.

Configure Your ColumN Your Way


KrosFlo® KR2i with Konduit

A proven turnkey benchtop system for lab-scale process development, the KrosFlo® KR2i Tangential Flow Filtration (TFF) System is fully integrated and easy to use with walkaway automation.

  • 2ml - 15L volume
  • 13 cm2 - 5000 cm2 filtration area

High Productivity Harvest

High Productivity Harvest (HPH) is a novel application developed by Repligen that enables you to harvest a fed-batch bioreactor in a fully sterile manner, while eliminating both centrifugation and depth filtration operations typically used for harvest/clarification. A single stage, closed process using the XCell ATF® device, the HPH application provides:

  • Higher yields compared to traditional harvest technologies

  • Up to a two-fold increase in protein production

  • A 0.2µm clarified harvest ready for either batch or continuous chromatography

"The DNA of our company is absolutely around customer first. Listening to what our customers are doing, what their needs are, what their pain points are, touches every facet of what we do."

Tony Hunt, President and CEO        

Join the REpligen Team

With offices and facilities in multiple locations, we are always looking for smart, driven, and enthusiastic individuals to join our growing team.

See Open Positions

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