Four Common Pitfalls to Avoid in UF/DF Setup and Scale-Up
Ultrafiltration Diafiltration (UF/DF) processes that look robust at the development scale often expose critical weaknesses during scale-up or tech transfer—resulting in capacity constraints, excessive manual intervention, delayed timelines, or manufacturing risk. In many cases, these issues trace back to early UF/DF decisions that seemed reasonable at the time but didn’t fully account for scalability, system design, or cross-functional alignment.
In this webinar, we’ll break down four of the most common—and costly—pitfalls in UF/DF setup and scale-up, including poor filter sizing and membrane selection, overreliance on manual operations, system design limitations, and breakdowns in communication between Process Development and MSAT teams. Through practical examples drawn from downstream workflows, we’ll show how these pitfalls emerge, why they persist, and how they impact process robustness and manufacturing success.
Viewers will leave with practical strategies to design more scalable UF/DF processes, reduce manual burden, improve system selection, and strengthen PD–MSAT collaboration—helping teams avoid late-stage surprises and enabling smoother tech transfer to manufacturing.
Avoid scale-up surprises with membrane selection strategies that are fit-for-purpose
Reduce manual burden and operational risk by understanding when automation and system design choices matter most for robust, scalable UF/DF operations
Enable smoother tech transfer by improving alignment and communication between Process Development and MSAT teams early in process design
