Advances in Bioprocessing Industry case studies on single-use, flexible and continuous bioprocessing
At Repligen bioprocessing seminars, thought leaders and professionals from around the world meet and review exciting new drivers of bioprocessing efficiency, learn from adopters of transformative technologies, evaluate risk landscapes and collaborate to help set the standards of modern bioproduction.
Registration and Coffee
Welcome and Overview
End-to-end Integrated Continuous Manufacture of Therapeutic Proteins: Key Technologies and Lessons Learned
Hang Zhou, Director of Biologics, Wuxi Apptec
Dr. Zhou currently is the Director of Biologics at Wuxi Apptec. He leads a team for perfusion process development of recombinant protein and mAb-based biotherapeutics, from R&D to GMP-compliant production scale, overcoming the challenge of long-term continuous perfusion culture with high cell-density, obtaining stable and good product quality. Before joining Wuxi Apptec, Dr.Zhou worked at commercial cell culture process development department of Genzyme Corporation, and participated in perfusion cell culture process development works of a series of enzyme and mAb-based pharmaceuticals. Dr. Zhou graduated from Chemical Engineering Department of Tsinghua University, and holds Ph.D. in chemical engineering from MIT.
Advantages of Using Pre-packed Columns in Purification Process Development
Connery Lin, Ph.D, Director of Downstream Process Development, CGB/Chempartner
Dr. Lin is currently the Director of Downstream Process Developing at CGB/ChemPartner. He brings 10 years’ experience of in biologics development and manufacturing with Assay development, fermentation, purification and formulation. Dr. Lin has set up PD/AD/QC labs and pilot/commercial single-use systems from 50L up to 2K. He previously held roles at JHL Biotech, PharmaEssentia, Purzer Pharmaceuticals and YungShin Pharma. Dr. Lin holds a Bachelor’s of Science degree from National Chung Hsing University, a Master’s in Chemical Engineering from Chung Yuan Christian University and a Ph.D. in Chemical Engineering from National Taiwan University.
What's New in Pre-packed Disposable Chromatography Technology?
Aidan Audouy, Sales Director, Asia, Repligen
Mr. Audouy is currently Asia Sales Director for Repligen. Based out of Singapore, he supports the rapidly expanding Asian market as the Repligen leading product portfolio continues to expand. Mr. Audouy began working in the bioprocess industry in 2002 and has worked with various technologies and has previously held roles at Constant Systems Ltd and Refine Technology. Mr. Audouy graduated from the Daventry Campus of Northampton College, Northants, UK with A-Levels in Physics, Electronics, French and English Literature.
Lunch and Networking
Novel Filtration Solutions for Gene therapy Bioprocessing
Haifeng Gao, Director of Process Development, Ctigen
Mr. Gao is currently the Process Manager for GMP production process development and pilot production of plasmid, lentivirus and CAR-T cells at the Suzhou Ctigen Medical Technology Co., Ltd. He brings 13 years’ experience of downstream biotherapeutic process development, pilot scale-up, technology transfer and CMO production (especially in CAR-T, monoclonal antibody, cell factors), participated in production technology transfer for Australia, India and England clinical trial applications, and has spent several years in team management. Mr.Gao previously held roles at JW Biotechnology, BioMabs and Jintao Biotechnology of Northern China Pharmaceutical group. Mr. Gao holds MSc in biochemical engineering from East China University of Science and Technology
Selection of a Flat Sheet TFF Cassette in Downstream Processing of a Recombinant Protein
Guodong Chang, CEO, Protogen
Mr. Guodong Chang is currently the Vice Director of National Engineering Laboratory of Anti-cancer protein drugs and also the CEO of Beijing Protgen Bioscience development Co.,Ltd., and it’s related companies. Mr. Chang has 20 years experiences of biotechnology and biopharmaceutical development, especially in recombinant protein therapeutics research and production application development. As leading scientist, developed several new drugs, which are successfully approved by China and/or EU market.
Performance and Economic Advantages of Single-use Flat Sheet Tangential Flow Filtration
David Bianchi, TFF Field Application Specialist, Repligen
Implementation of single-use alternatives in tangential flow filtration (TFF), a critical step in concentration and diafiltration (buffer exchange), is becoming platform in downstream bioprocessing. Repligen TangenX™ SIUS™ Single-use Cassettes are the first purpose-built cassettes designed for tangential flow filtration. This presentation will demonstrate how deploying these innovative cassettes can help reduce filter cost by 80%, reduce labor costs by 50%, and reduce buffer and water usage by 75% when compared to traditional reusable cassettes.
Mr. Bianchi is currently the Field Applications Specialist for Repligen downstream TFF products. He brings over 20 years of experience in process filtration and separation with a significant portion of that time focused on Tangential Flow Filtration applications utilizing flat sheet cassettes and hollow fiber modules. Mr. Bianchi has held various technical positions supporting Pall Corporation, Spectrum Laboratories, FloDesign Sonics and TangenX™. He holds a Bachelor of Science degree in Chemistry from Worcester Polytechnic Institute.
LIVE DEMO: Fully Automated TFF Using Flat Sheet Cassettes: How to set up the KR2i TFF System with TangenX™ Flat Sheet Cassettes
Discover More Seminars/Technical Roadshows