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Gene Therapy Manufacturing 2.0 White Paper
By René Gantier, PhD, Director of Gene Therapy Technologies, Repligen Corporation  Repligen Corporation
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DOC0160 SoloVPE V3 21 CFR Part 11 Compliance Position White Paper
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DOC0433 MAVERICK White Paper - De novo Approaches for Bioprocess Parameter Estimation
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DOC0198 ViPER ANLYTX 21 CFR Part 11 Compliance Position Software White Paper
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Impact of N-1 Seed Train Intensification on Viral Vector Production White Paper
By Ly Truong, Riaj Mahamud, Benedict Kang, Keen Chung, Rene Gantier Repligen Corporation
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AAV Studies Deploying a Closed, Irradiated, Single-use Flat Sheet TFF Device White Paper
By David Bianchi, Carl Breuning, Michael LaBreck, Shelly Parra, Mary Jo Wojtusik, Repligen Corporation  Alex Meola, Michael Mercaldi, Thomas Thiers, Homology, Medicines Inc.  Repligen Corporation Homology, Medicines Inc.
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Evaluating DNA purity ratio determination with the CTech™ SoloVPE® System White Paper
Spectrophotometric analysis is one of the most common techniques used to quantitate nucleic acids in a solution. However, traditional fixed-pathlength spectrophotometers have limitations when determining the purity ratios of these molecules. In this study, the CTechTM SoloVPE system assessed theoretical DNA purity ratios by utilizing its variable pathlength method, known as Slope Spectroscopy. The method was evaluated by assessing the specificity, intermediate precision, repeatability, linearity, and accuracy of the theoretical purity ratios. The observed purity ratios from the SoloVPE system demonstrated great comparison to the theoretical purity ratios, verifying the SoloVPE system’s slope spectroscopy method to be preferable for this application. Authors: Nigel Herbert, Drusha Purohit, Hannah Mignault
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Reducing Clinical-Phase Manufacturing Costs: Collaborating for Savings without Compromising Quality or Performance White Paper
By Dana Pentia et al. BioProcess International 14(1)
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Reducing Error Propagation in TFF Processes using the KrosFlo® KR2i RPM™ System White Paper
Oleksandr Karpenko, Repligen; Westley Blacklock, Repligen; Jigar Patel, Repligen; Brandon Goldberg, Repligen; Joe Ferraiolo, Repligen
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Implementation of the CTech™ SoloVPE® Technology for Protein Concentration Measurement of Monoclonal Antibodies White Paper